CymitQuimica logo

CAS 103478-58-6

:

fmoc-N-methyl-D-valine

Description:
Fmoc-N-methyl-D-valine is a derivative of the amino acid valine, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protective group attached to the nitrogen of the amino group and a methyl group on the alpha carbon. This compound is commonly used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), due to the stability of the Fmoc group under basic conditions and its ease of removal under mild acidic conditions. Fmoc-N-methyl-D-valine exhibits properties typical of amino acids, such as the ability to form peptide bonds, and it contributes to the hydrophobic character of peptides. Its stereochemistry, being D-valine, influences the conformation and biological activity of the resulting peptides. The compound is typically a white to off-white solid and is soluble in organic solvents like dimethyl sulfoxide (DMSO) and methanol. Safety data should be consulted for handling, as with all chemical substances, to ensure proper laboratory practices.
Formula:C21H23NO4
InChI:InChI=1/C21H23NO4/c1-13(2)19(20(23)24)22(3)21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,12H2,1-3H3,(H,23,24)/t19-/m1/s1
SMILES:CC(C)[C@H](C(=O)O)N(C)C(=O)OCC1c2ccccc2c2ccccc12
Synonyms:
  • Fmoc-N-Me-D-Val-OH
  • N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-valine
  • Fmoc-D-N-Me-Val-OH
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.