CAS 103478-63-3

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-leucine

Description:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-leucine, commonly referred to as Fmoc-D-Leu-OMe, is a derivative of the amino acid leucine, modified with a fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is primarily utilized in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the Fmoc group serves as a protective moiety for the amino group, allowing for selective deprotection and coupling reactions. The presence of the methyl group on the nitrogen atom enhances the steric bulk and can influence the peptide's conformation and solubility. Fmoc-D-Leu-OMe is characterized by its stability under basic conditions, making it suitable for various synthetic protocols. Additionally, it exhibits good solubility in organic solvents, which is advantageous during the synthesis process. The compound's structure contributes to its role in facilitating the formation of peptides with specific sequences and properties, making it a valuable tool in the fields of biochemistry and medicinal chemistry.

Formula: C₂₂H₂₅NO₄

InChI: InChI=1/C22H25NO4/c1-14(2)12-20(21(24)25)23(3)22(26)27-13-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,14,19-20H,12-13H2,1-3H3,(H,24,25)/t20-/m1/s1

InChI key: InChIKey=BUJQSIPFDWLNDC-HXUWFJFHSA-N

SMILES: C(OC(N([C@H](CC(C)C)C(O)=O)C)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• (2R)-2-[9H-Fluoren-9-ylmethoxycarbonyl(methyl)amino]-4-methylpentanoic acid
• (R)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl](methyl)amino]-4-methylpentanoic acid
• <span class="text-smallcaps">D</span>-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
• Fmoc-D-Meleu-Oh
• Fmoc-D-N-Me-Leu-OH
• Fmoc-N-Alpha-Methyl-D-Leucine
• Fmoc-N-Me-D-Leu-Oh
• Fmoc-N-Methyl-D-Leucine 98+%
• N-(9-Fluorenylmethoxycarbonyl)-N-methyl-<span class="text-smallcaps">D</span>-leucine
• N-Alpha-(9-Fluorenylmethoxycarbonyl)-N-Alpha-Methyl-D-Leucine
• N-Alpha-(9-Fluorenylmethyloxycarbonyl)-N-Alpha-Methyl-D-Leucine
• N-Alpha-Fmoc-N-Alpha-Methyl-D-Leucine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-<span class="text-smallcaps">D</span>-leucine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-leucine
• N-(9-Fluorenylmethoxycarbonyl)-N-methyl-D-leucine
• D-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
• FMOC-N-METHYL-D-LEUCINE

N-Fmoc-N-methyl-D-leucine, 97%

CAS: 103478-63-3

Tripeptides were prepared by means of coupling of N-Fmoc-N-methyl-D-leucine. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or

Formula: C₂₂H₂₅NO₄

Purity: 97%

Molecular weight: 367.45

Ref: 02-H63895

FMoc-N-Me-D-Leu-OH

CAS: 103478-63-3

Formula: C₂₂H₂₅NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 367.4382

Ref: IN-DA003QNQ

Fmoc-N-methyl-D-leucine

CAS: 103478-63-3

Fmoc-N-methyl-D-leucine

Purity: 98%

Molecular weight: 367.44g/mol

Ref: 54-OR963073

Fmoc-N-Me-D-Leu-OH

CAS: 103478-63-3

Molecular weight: 367.44

Ref: 7W-GM1514

fmoc-d-n-me-leu-oh

CAS: 103478-63-3

Formula: C₂₂H₂₅NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 367.445

Ref: 10-F045417