CAS 10356-76-0: 5-Fluoro-2'-deoxycytidine
Description:5-Fluoro-2'-deoxycytidine (FdC) is a nucleoside analog of cytidine, characterized by the substitution of a fluorine atom at the 5-position of the pyrimidine ring. This modification enhances its antiviral and antitumor properties, making it a subject of interest in cancer and viral therapy research. FdC is typically a white to off-white crystalline powder, soluble in water and polar organic solvents, which facilitates its use in various formulations. The compound acts by interfering with DNA synthesis, thereby inhibiting the proliferation of cancer cells and certain viruses. Its mechanism of action involves incorporation into DNA, leading to chain termination during replication. FdC has been studied for its efficacy against various malignancies and viral infections, including HIV. Safety and toxicity profiles are critical in its application, as with any chemotherapeutic agent. Overall, 5-Fluoro-2'-deoxycytidine represents a significant advancement in the development of targeted therapies in oncology and virology.
Formula:C9H12FN3O4
InChI:InChI=1S/C9H12FN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5-,6+,7+/m0/s1
InChI key:InChIKey=IDYKCXHJJGMAEV-RRKCRQDMSA-N
SMILES:O=C1N=C(N)C(F)=CN1C2OC(CO)C(O)C2
- Synonyms:
- 2'-Deoxy-5-Fluorocytidine
- 2'-Deoxy-5-fluorcytidine
- 4-amino-1-(2-deoxypentofuranosyl)-5-fluoropyrimidin-2(1H)-one
- 4-amino-1-[(3xi)-2-deoxy-beta-D-glycero-pentofuranosyl]-5-fluoropyrimidin-2(1H)-one
- 5-Fluor-desoxycytidin
- 5-Fluor-desoxycytidin [German]
- 5-Fluorodeoxycytidine
- Brn 0619209
- Cytidine, 2'-deoxy-5-fluoro-
- FCdR
- See more synonyms
- Fluorodeoxycytidine
- Nsc 48006
- Ro 5-1090
