CAS 10356-76-0

5-Fluoro-2'-deoxycytidine

Description:

5-Fluoro-2'-deoxycytidine (FdC) is a nucleoside analog of cytidine, characterized by the substitution of a fluorine atom at the 5-position of the pyrimidine ring. This modification enhances its antiviral and antitumor properties, making it a subject of interest in cancer and viral therapy research. FdC is typically a white to off-white crystalline powder, soluble in water and polar organic solvents, which facilitates its use in various formulations. The compound acts by interfering with DNA synthesis, thereby inhibiting the proliferation of cancer cells and certain viruses. Its mechanism of action involves incorporation into DNA, leading to chain termination during replication. FdC has been studied for its efficacy against various malignancies and viral infections, including HIV. Safety and toxicity profiles are critical in its application, as with any chemotherapeutic agent. Overall, 5-Fluoro-2'-deoxycytidine represents a significant advancement in the development of targeted therapies in oncology and virology.

Formula: C₉H₁₂FN₃O₄

InChI: InChI=1/C9H12FN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5-,6+,7+/m0/s1

InChI key: InChIKey=IDYKCXHJJGMAEV-RRKCRQDMSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(F)C(N)=N1

Synonyms:

• 2'-Deoxy-5-Fluorocytidine
• 2'-Deoxy-5-fluorcytidine
• 4-amino-1-(2-deoxypentofuranosyl)-5-fluoropyrimidin-2(1H)-one
• 4-amino-1-[(3xi)-2-deoxy-beta-D-glycero-pentofuranosyl]-5-fluoropyrimidin-2(1H)-one
• 5-Fluor-desoxycytidin
• 5-Fluor-desoxycytidin [German]
• 5-Fluorodeoxycytidine
• Brn 0619209
• Cytidine, 2'-deoxy-5-fluoro-
• FCdR
• Fluorodeoxycytidine
• Nsc 48006
• Ro 5-1090
• 5-Fluoro-2-deoxycytidine
• 5-Fluoro-2′-deoxycytidine

2'-Deoxy-5-fluorocytidine

CAS: 10356-76-0

Formula: C₉H₁₂FN₃O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 245.21

Ref: 3B-D3642

4-Amino-5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

CAS: 10356-76-0

Formula: C₉H₁₂FN₃O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 245.2077

Ref: IN-DA0085MF

5-Deoxy-5-fluorocytidine (5-DFCR)

CAS: 10356-76-0

Formula: C₉H₁₂FN₃O₄

Molecular weight: 245.21

Ref: 7W-GP6521

5-Fluoro-2'-Deoxycytidine

CAS: 10356-76-0

5-Fluoro-2'-Deoxycytidine

Purity: 98%

Molecular weight: 245.21g/mol

Ref: 54-PC105285

5-Fluoro-2'-deoxycytidine

CAS: 10356-76-0

5-Fluoro-2'-deoxycytidine

Purity: ≥95%

Molecular weight: 245.21g/mol

Ref: 54-BUP12947

5-Fluoro-2'-deoxycytidine

CAS: 10356-76-0

5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .

Formula: C₉H₁₂FN₃O₄

Purity: 97.91%

Color and Shape: Fine White Powder

Molecular weight: 245.21

Ref: TM-T7718

2'-Deoxy-5-fluorocytidine

CAS: 10356-76-0

2'-Deoxy-5-fluorocytidine is a methyltransferase inhibitor that inhibits the activity of DNA methyltransferases. It has been shown to inhibit the activity of DNA methyltransferases in vitro and in vivo, leading to tumor cell death. 2'-Deoxy-5-fluorocytidine has been shown to target intracellular targets, such as histones and ribosomes, which are involved in cancer development. The toxicity of this drug has been studied extensively and it has been shown to have low toxicity in mice. This drug is not toxic for normal cells or animals when administered at high doses.

Formula: C₉H₁₂FN₃O₄

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 245.21 g/mol

Ref: 3D-ND10199

5-Fluorodeoxycytidine

CAS: 10356-76-0

Formula: C₉H₁₂FN₃O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 245.21

Ref: 10-F222059