CAS 103560-62-9

4-Oxo-2-(E)-nonenal

Description:

4-Oxo-2-(E)-nonenal, also known as 4-oxo-2-nonenal, is an organic compound characterized by its structure as an α,β-unsaturated aldehyde. It features a nonenal backbone with a ketone functional group at the fourth carbon and an alkene configuration at the second carbon, specifically in the trans (E) orientation. This compound is typically a yellowish liquid at room temperature and is known for its strong, pungent odor. It is soluble in organic solvents and has limited solubility in water. 4-Oxo-2-(E)-nonenal is of interest in various fields, including food chemistry and biochemistry, due to its role as a potential flavor compound and its involvement in lipid peroxidation processes, which can lead to oxidative stress in biological systems. Additionally, it has been studied for its potential effects on cellular signaling and its implications in various health-related contexts. Safety data indicates that it should be handled with care, as it may be irritating to the skin and eyes.

Formula: C₉H₁₄O₂

InChI: InChI=1S/C9H14O2/c1-2-3-4-6-9(11)7-5-8-10/h5,7-8H,2-4,6H2,1H3/b7-5+

InChI key: InChIKey=SEPPVOUBHWNCAW-FNORWQNLSA-N

SMILES: C(C(/C=C/C=O)=O)CCCC

Synonyms:

• (+/-)-4-Oxo-2E-Nonenal
• (2E)-4-Oxo-2-nonenal
• (2E)-4-oxonon-2-enal
• (E)-4-Oxo-2-nonenal
• 2-Nonenal, 4-oxo-, (2E)-
• 2-Nonenal, 4-oxo-, (E)-
• 4-Oxo-2-(E)-nonenal
• 4-Oxo-2-Nonenal

4-ONE

CAS: 103560-62-9

Formula: C₉H₁₄O₂

Purity: 95%

Molecular weight: 154.2063

Ref: IN-DA008RDX

4-oxo-2-Nonenal

CAS: 103560-62-9

4-Hydroxy Nonenal and 4-oxo-2-Nonenal are lipid peroxidation byproducts, signaling oxidative stress and possibly causing mutagenesis.

Formula: C₉H₁₄O₂

Color and Shape: Solid

Molecular weight: 154.209

Ref: TM-T35646

4-oxo-2(E)-nonenal

CAS: 103560-62-9

Formula: C9H14O2

Purity: >98%

Color and Shape: In solution, Methyl acetate

Molecular weight: 154.21

Ref: 48-12-0922

(2E)-4-Oxonon-2-enal

CAS: 103560-62-9

The olefin (2E)-4-oxonon-2-enal is a reactive metabolite that can be formed by the oxidation of polyunsaturated fatty acids. This process is mediated by the enzyme cytochrome P450 2E1. The binding of this metabolite to macrophages leads to an increase in intracellular calcium concentration and genotoxic effects, which may lead to oxidative injury. Metabolism of 2E-4-oxonon-2-enal leads to the formation of malondialdehyde, which is detoxified by enzymatic reactions with glutathione and superoxide dismutase. The physiological function of 2E-4-oxonon-2-enal has not been fully elucidated, but it may play a role in cellular signaling and energy metabolism.

Formula: C₉H₁₄O₂

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 154.21 g/mol

Ref: 3D-FO172477