CAS 1035638-91-5

N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide

CAS: 1035638-91-5

Formula: C₁₈H₁₄ClFN₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 372.7808

Ref: IN-DA01ENKO

N-[4-[(3-Chloro-4-Fluorophenyl)Amino]-7-Methoxy-6-Quinazolinyl]-2-Propenamide

CAS: 1035638-91-5

N-[4-[(3-Chloro-4-Fluorophenyl)Amino]-7-Methoxy-6-Quinazolinyl]-2-Propenamide

Purity: 98%

Molecular weight: 372.78g/mol

Ref: 54-PC108586

PF-6274484

CAS: 1035638-91-5

PF-6274484

Purity: ≥95%

Molecular weight: 372.78g/mol

Ref: 54-BUP09757

PF-6274484

CAS: 1035638-91-5

PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M and WT-EGFR, respectively.

Formula: C₁₈H₁₄ClFN₄O₂

Purity: 97.71%

Color and Shape: Solid

Molecular weight: 372.78

Ref: TM-T22396

PF-6274484

CAS: 1035638-91-5

PF-6274484 is a histone methylation inhibitor that binds to the drug target and inhibits histone methyltransferases. This inhibition leads to decreased expression of genes associated with cancer, including genes that regulate cell cycle progression, proliferation, invasion, and metastasis. PF-6274484 also induces apoptosis in tumor cells by inhibiting the growth factor signal transduction pathway. PF-6274484 has been shown to bind specifically to enteroendocrine cells in the gastrointestinal tract and inhibit their growth. PF-6274484 has been shown to have minimal effects on other mammalian cell types.

Formula: C₁₈H₁₄ClFN₄O₂

Purity: Min. 95%

Molecular weight: 372.78 g/mol

Ref: 3D-KRB63891