CAS 1035654-66-0

(4S,4aS,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-[(methoxymethylamino)methyl]-1,11-dioxo-2-naphthacenecarboxamide

Description:

The chemical substance with the name "(4S,4aS,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-[(methoxymethylamino)methyl]-1,11-dioxo-2-naphthacenecarboxamide" and CAS number "1035654-66-0" is a complex organic compound characterized by its multi-ring structure and multiple functional groups. It features a naphthacene backbone, which contributes to its potential biological activity. The presence of hydroxyl groups indicates that it may exhibit hydrogen bonding capabilities, influencing its solubility and reactivity. The dimethylamino group suggests potential interactions with biological systems, possibly affecting its pharmacological properties. Additionally, the methoxymethylamino substituent may enhance its lipophilicity, impacting its absorption and distribution in biological contexts. The stereochemistry indicated by the specific configuration at various chiral centers suggests that the compound may exhibit stereoselective behavior in biological interactions. Overall, this compound's structural complexity and functional diversity position it as a candidate for further investigation in medicinal chemistry and pharmacology.

Formula: C₂₄H₂₉N₃O₈

InChI: InChI=1S/C24H29N3O8/c1-26(2)18-13-8-11-7-12-10(9-27(3)35-4)5-6-14(28)16(12)19(29)15(11)21(31)24(13,34)22(32)17(20(18)30)23(25)33/h5-6,11,13,18,28,30-31,34H,7-9H2,1-4H3,(H2,25,33)/t11-,13-,18-,24-/m0/s1

InChI key: InChIKey=PQJQFLNBMSCUSH-SBAJWEJLSA-N

SMILES: O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)(C[C@]3(C(=C2O)C(=O)C=4C(C3)=C(CN(OC)C)C=CC4O)[H])[H]

Synonyms:

• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-[(methoxymethylamino)methyl]-1,11-dioxo-, (4S,4aS,5aR,12aS)-
• P 005672
• (4S,4aS,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-[(methoxymethylamino)methyl]-1,11-dioxo-2-naphthacenecarboxamide
• Sarecycline
• Seysara

Sarecycline

CAS: 1035654-66-0

Formula: C₂₄H₂₉N₃O₈

Color and Shape: Yellow Solid

Molecular weight: 487.51

Ref: 4Z-M-3434

Sarecycline free base

CAS: 1035654-66-0

Sarecycline free base (P005672) is a tetracycline-derived, narrow-spectrum antibiotic.

Formula: C₂₄H₂₉N₃O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 487.5

Ref: TM-T28661

Sarecycline-d6 Hydrochloride

Controlled Product

CAS: 1035654-66-0, 1035979-44-2

Formula: C₂₄H₂₃D₆N₃O₈•HCl

Color and Shape: Neat

Molecular weight: 530.01

Ref: TR-S140522

Sarecycline

CAS: 1035654-66-0

Sarecycline is a tetracycline-class antibiotic, which is derived from naturally occurring tetracycline antibiotics. Its mode of action involves inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to nascent peptide chains. This specific mechanism disrupts bacterial growth, making Sarecycline effective against certain strains of bacteria implicated in dermatological conditions.

Formula: C₂₄H₂₉N₃O₈

Purity: Min. 95 Area-%

Molecular weight: 487.5 g/mol

Ref: 3D-FS180986