CAS 103587-51-5

O-[(1,1-dimethylethyl)diphenylsilyl]-Hydroxylamine

Description:

O-[(1,1-dimethylethyl)diphenylsilyl]-hydroxylamine, with the CAS number 103587-51-5, is a chemical compound characterized by the presence of a hydroxylamine functional group attached to a silyl ether moiety. This compound features a bulky tert-butyl group and two phenyl groups bonded to a silicon atom, which contributes to its steric hindrance and potential reactivity. Hydroxylamines are known for their ability to act as nucleophiles and can participate in various organic reactions, including the formation of oximes and the reduction of carbonyl compounds. The presence of the silyl group may enhance the stability of the hydroxylamine, making it less prone to oxidation compared to simpler hydroxylamines. Additionally, this compound may exhibit unique solubility properties due to its bulky structure, influencing its behavior in different solvents. Overall, O-[(1,1-dimethylethyl)diphenylsilyl]-hydroxylamine is of interest in synthetic organic chemistry, particularly in the development of new methodologies for functional group transformations.

Formula: C₁₆H₂₁NOSi

Synonyms:

• Hydroxylamine, O-[(1,1-dimethylethyl)diphenylsilyl]-

O-(tert-Butyldiphenylsilyl)hydroxylamine

CAS: 103587-51-5

Formula: C₁₆H₂₁NOSi

Purity: 95%

Color and Shape: Solid

Molecular weight: 271.4295

Ref: IN-DA003TF1

O-(tert-Butyldiphenylsilyl)hydroxylamine

CAS: 103587-51-5

O-(tert-Butyldiphenylsilyl)hydroxylamine

Purity: 98%

Color and Shape: Solid

Molecular weight: 271.43g/mol

Ref: 54-OR964958

O-(tert-Butyldiphenylsilyl)hydroxylamine

CAS: 103587-51-5

Formula: C₁₆H₂₁NOSi

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 271.44

Ref: 3B-B5999

O-(TERT-BUTYLDIPHENYLSILYL)HYDROXYLAMINE

CAS: 103587-51-5

Formula: C₁₆H₂₁NOSi

Purity: 97%

Color and Shape: No data available.

Molecular weight: 271.435

Ref: 10-F387109

O-t-Butyldiphenylsilylhydroxylamine

Controlled Product

CAS: 103587-51-5

Applications O-t-Butyldiphenylsilylhydroxylamine is an intermediate in synthesizing N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt (H996005), which is a metabolite of Vortioxetine (V766000, HBr); a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.
References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013); Uldam, H.K., et al.: Drug Metab. Dispos., 39, 2264 (2011);

Formula: C₁₆H₂₁NOSi

Color and Shape: Neat

Molecular weight: 271.43

Ref: TR-B820030