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CAS 103656-40-2

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24-homo-1,25-dihydroxyvitamin D3

Description:
24-Homo-1,25-dihydroxyvitamin D3, identified by its CAS number 103656-40-2, is a synthetic analog of vitamin D3, specifically designed to explore the biological effects of vitamin D metabolites. This compound features a modified side chain at the 24-position, which alters its interaction with vitamin D receptors. It exhibits similar biological activity to 1,25-dihydroxyvitamin D3, the active form of vitamin D, influencing calcium and phosphate metabolism, and promoting bone health. The structural modifications enhance its stability and bioavailability, making it a valuable tool in research related to bone diseases and calcium homeostasis. Additionally, it may have implications in the study of various conditions, including osteoporosis and certain cancers, due to its role in regulating cell proliferation and differentiation. As a fat-soluble vitamin, it is typically administered in a lipid-based formulation to ensure optimal absorption in biological systems. Overall, 24-homo-1,25-dihydroxyvitamin D3 serves as an important compound for understanding vitamin D's physiological roles and therapeutic potential.
Formula:C28H46O3
InChI:InChI=1/C28H46O3/c1-19(9-6-7-15-27(3,4)31)24-13-14-25-21(10-8-16-28(24,25)5)11-12-22-17-23(29)18-26(30)20(22)2/h11-12,19,23-26,29-31H,2,6-10,13-18H2,1,3-5H3/b21-11+,22-12+/t19?,23-,24-,25+,26+,28-/m1/s1
Synonyms:
  • 24-Homo-calcitriol
  • 1,3-Cyclohexanediol, 4-methylene-5-(2-(octahydro-1-(6-hydroxy-1,6-dimethylheptyl)-7a-methyl-4H-inden-4-ylidene)ethylidene)-, (1R-(1alpha(R*),3abeta,4E(1R*,3S*,5Z),7aalpha))-
  • (1R,3S,5E)-5-[(2E)-2-[(1R,3aS,7aR)-1-(6-hydroxy-1,6-dimethyl-heptyl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol
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