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Fasudil

CAS 103745-39-7: Fasudil

Description:Fasudil is a pharmacological agent primarily recognized for its role as a selective inhibitor of Rho-kinase, an enzyme involved in various cellular processes, including smooth muscle contraction and cell migration. Its chemical formula is C14H18N4O2, and it is classified as a small molecule. Fasudil is often utilized in the treatment of conditions such as cerebral vasospasm following subarachnoid hemorrhage and has shown potential in various other therapeutic areas, including cardiovascular diseases and neuroprotection. The substance is typically administered in the form of a hydrochloride salt, enhancing its solubility and bioavailability. Fasudil exhibits properties such as anti-inflammatory effects and the ability to improve blood flow by relaxing vascular smooth muscle. Its mechanism of action involves the modulation of the RhoA/Rho-kinase signaling pathway, which plays a crucial role in regulating vascular tone and remodeling. As with any pharmacological agent, the use of Fasudil may be accompanied by side effects, and its safety profile is an important consideration in clinical applications.

Formula:C14H19Cl2N3O2S

InChI:InChI=1S/C14H17N3O2S/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14/h1,3-5,7,11,15H,2,6,8-10H2

InChI key:InChIKey=NGOGFTYYXHNFQH-UHFFFAOYSA-N

SMILES:O=S(=O)(C1=CC=CC=2C=NC=CC21)N3CCNCCC3

  • Synonyms:
  • (5-Isoquinolinesulfonyl)Homopiperazine
  • 1-(5-Isoquinolinesulfonyl)homopiperazine
  • 1-(5-Isoquinolinesulphonyl)homopiperazine
  • 1-(5-Isoquinolinylsulfonyl)homopiperazine
  • 103745-39-7
  • 1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-
  • 5-(1,4-Diazepan-1-Ylsulfonyl)Isoquinoline Dihydrochloride
  • 5-(1,4-Diazepan-1-Ylsulfonyl)Isoquinoline Hydrochloride (1:1)
  • 5-(1,4-Diazepan-1-ylsulfonyl)isoquinoline
  • 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]isoquinoline
  • See more synonyms
  • At 877
  • Ha 1077
  • Hexahydro-1-(5-isoquinolinesulfonyl)-1H-1,4-diazepine
  • N-(5-Isoquinolinesulfonyl)-1,4-perhydrodiazepine
  • isoquinoline, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-
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Found 7 products.

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Ref: 3B-F0839

100mg95.00 €
Estimated delivery in United States, on Tuesday 25 Feb 2025
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Fasudil, 98+%

CAS:103745-39-7

Ref: 02-J63525

10mgTo inquire
Estimated delivery in United States, on Wednesday 26 Feb 2025
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Fasudil

CAS:103745-39-7

Ref: 7W-GP2490

Undefined sizeTo inquire
Estimated delivery in United States, on Wednesday 5 Mar 2025
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Fasudil

CAS:103745-39-7

Ref: TM-T1606

50mg39.00 €
100mg49.00 €
200mg67.00 €
500mg105.00 €
Estimated delivery in United States, on Wednesday 5 Mar 2025
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Fasudil

CAS:103745-39-7

Ref: TR-F150023

100mg111.00 €
Estimated delivery in United States, on Friday 14 Mar 2025
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Fasudil

CAS:103745-39-7

Ref: 3D-DEA74539

50mg461.00 €
500mg1,083.00 €
Estimated delivery in United States, on Tuesday 15 Apr 2025
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