The chemical substance with the name "N3-[4-[4-(1R,2R,4S)-Bicyclo[2.2.1]hept-2-yl-1-piperazinyl]phenyl]-1-(2-chloro-7-methylthieno[3,2-d]pyrimidin-4-yl)-1H-1,2,4-triazole-3,5-diamine" and CAS number "1037798-41-6" is a complex organic compound characterized by its multi-cyclic structure and the presence of various functional groups. It features a bicyclic system, which contributes to its three-dimensional conformation, and a piperazine moiety that may influence its biological activity and solubility. The presence of a thieno[3,2-d]pyrimidine ring and a triazole group suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. The chlorine and methyl substituents can affect the compound's reactivity and interaction with biological targets. Overall, this compound's intricate structure and diverse functional groups indicate potential for specific biological activity, making it a candidate for further research in drug development and therapeutic applications.

N3-[4-[4-(1R,2R,4S)-Bicyclo[2.2.1]hept-2-yl-1-piperazinyl]phenyl]-1-(2-chloro-7-methylthieno[3,2-d]pyrimidin-4-yl)-1H-1,2,4-triazole-3,5-diamine

1037798-41-6: The chemical substance with the name "N3-[4-[4-(1R,2R,4S)-Bicyclo[2.2.1]hept-2-yl-1-piperazinyl]phenyl]-1-(2-chloro-7-methylthieno[3,2-d]pyrimidin-4-yl)-1H-1,2,4-triazole-3,5-diamine" and CAS number "1037798-41-6" is a complex organic compound characterized by its multi-cyclic structure and the presence of various functional groups. It features a bicyclic system, which contributes to its three-dimensional conformation, and a piperazine moiety that may influence its biological activity and solubility. The presence of a thieno[3,2-d]pyrimidine ring and a triazole group suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. The chlorine and methyl substituents can affect the compound's reactivity and interaction with biological targets. Overall, this compound's intricate structure and diverse functional groups indicate potential for specific biological activity, making it a candidate for further research in drug development and therapeutic applications.

<p>R916562 is an orally active and selective Axl/VEGF-R2 inhibitor with IC50s of 136 nM and 24 nM, respectively. R916562 has anti-angiogenesis and anti-metastasis.</p>

CAS 1037798-41-6

N3-[4-[4-(1R,2R,4S)-Bicyclo[2.2.1]hept-2-yl-1-piperazinyl]phenyl]-1-(2-chloro-7-methylthieno[3,2-d]pyrimidin-4-yl)-1H-1,2,4-triazole-3,5-diamine

R916562

Ref: TM-T12650