CAS 103882-85-5: 3Epigemcitabine
Description:3-Epigemcitabine, with the CAS number 103882-85-5, is a nucleoside analog that is primarily used in the field of cancer treatment. It is a derivative of gemcitabine, which is a well-known chemotherapeutic agent. The structure of 3-epigemcitabine features a modified sugar moiety that enhances its stability and efficacy against certain types of cancer cells. This compound exhibits antitumor activity by interfering with DNA synthesis and repair, ultimately leading to apoptosis in rapidly dividing cells. Its mechanism of action involves incorporation into DNA, which disrupts normal replication processes. Additionally, 3-epigemcitabine has been studied for its potential to overcome resistance mechanisms that cancer cells develop against traditional therapies. The pharmacokinetics of this compound suggest that it may have improved bioavailability and reduced toxicity compared to its parent compound. Ongoing research continues to explore its therapeutic potential and optimal dosing regimens in various cancer types.
Formula:C9H11F2N3O4
InChI:InChI=1/C9H11F2N3O4/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17)/t4-,6?,7-/m1/s1
- Synonyms:
- 4-Amino-1-(Deoxy-2,2-difluoro-D-threo-pentofuranosyl)-2(1H)-pyrimidinon
- (Gemcitabine Impurity
- 3’-Epi Gemcitabine (Gemcitabine Impurity)
- 4-Amino-1-(Deoxy-2,2-difluoro-D-threo-pentofuranosyl)-2(1H)-pyrimidinone
- 4-amino-1-[(2R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
![discount label](https://static.cymitquimica.com/public/img/discount.png)
Ref: 4Z-G-2619
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
![discount label](https://static.cymitquimica.com/public/img/discount.png)
3’-Epi Gemcitabine
Ref: TR-E588520
1mg | 964.00 € | ||
500µg | 547.00 € | ||
2500µg | 1,574.00 € |
![discount label](https://static.cymitquimica.com/public/img/discount.png)
3'-Epi gemcitabine
Ref: 3D-NE22706
1mg | 1,536.00 € | ||
2mg | 2,363.00 € | ||
5mg | 4,544.00 € |