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3Epigemcitabine

CAS 103882-85-5: 3Epigemcitabine

Description:3-Epigemcitabine, with the CAS number 103882-85-5, is a nucleoside analog that is primarily used in the field of cancer treatment. It is a derivative of gemcitabine, which is a well-known chemotherapeutic agent. The structure of 3-epigemcitabine features a modified sugar moiety that enhances its stability and efficacy against certain types of cancer cells. This compound exhibits antitumor activity by interfering with DNA synthesis and repair, ultimately leading to apoptosis in rapidly dividing cells. Its mechanism of action involves incorporation into DNA, which disrupts normal replication processes. Additionally, 3-epigemcitabine has been studied for its potential to overcome resistance mechanisms that cancer cells develop against traditional therapies. The pharmacokinetics of this compound suggest that it may have improved bioavailability and reduced toxicity compared to its parent compound. Ongoing research continues to explore its therapeutic potential and optimal dosing regimens in various cancer types.

Formula:C9H11F2N3O4

InChI:InChI=1/C9H11F2N3O4/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17)/t4-,6?,7-/m1/s1

  • Synonyms:
  • 4-Amino-1-(Deoxy-2,2-difluoro-D-threo-pentofuranosyl)-2(1H)-pyrimidinon
  • (Gemcitabine Impurity
  • 3’-Epi Gemcitabine (Gemcitabine Impurity)
  • 4-Amino-1-(Deoxy-2,2-difluoro-D-threo-pentofuranosyl)-2(1H)-pyrimidinone
  • 4-amino-1-[(2R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
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Found 4 products.

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Ref: 7W-GN7762

Undefined sizeTo inquire
Estimated delivery in United States, on Friday 28 Feb 2025
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Ref: 4Z-G-2619

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Estimated delivery in United States, on Friday 28 Feb 2025
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3’-Epi Gemcitabine

CAS:103882-85-5

Ref: TR-E588520

1mg964.00 €
500µg547.00 €
2500µg1,574.00 €
Estimated delivery in United States, on Wednesday 9 Apr 2025
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3'-Epi gemcitabine

CAS:103882-85-5

Ref: 3D-NE22706

1mg1,536.00 €
2mg2,363.00 €
5mg4,544.00 €
Estimated delivery in United States, on Thursday 10 Apr 2025
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