CAS 103883-03-0

8,14-Methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol,2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R,3S,8S,14R,15R)-

Description:

The chemical substance known as "8,14-Methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol,2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R,3S,8S,14R,15R)-" with CAS number 103883-03-0 is a complex organic compound characterized by its intricate polycyclic structure, which includes multiple fused rings and hydroxyl groups. This compound features a benzopyrano framework, indicating a connection between benzene and pyran rings, and is further modified by the presence of dioxocin and multiple hydroxyl (–OH) functional groups, contributing to its potential solubility and reactivity. The stereochemistry, denoted by the (2R,3S,8S,14R,15R) configuration, suggests specific spatial arrangements of atoms that can influence its biological activity and interactions. Such compounds are often studied for their potential pharmacological properties, including antioxidant and anti-inflammatory effects, due to the presence of multiple phenolic structures. Overall, this substance exemplifies the complexity and diversity found in organic chemistry, particularly in the realm of natural product derivatives.

Formula: C₃₀H₂₄O₁₂

InChI: InChI=1S/C30H24O12/c31-13-7-20(37)24-22(8-13)41-30(12-2-4-16(33)19(36)6-12)29(39)26(24)25-23(42-30)10-17(34)14-9-21(38)27(40-28(14)25)11-1-3-15(32)18(35)5-11/h1-8,10,21,26-27,29,31-39H,9H2/t21-,26+,27+,29+,30-/m0/s1

InChI key: InChIKey=NSEWTSAADLNHNH-TXZJYACMSA-N

SMILES: O[C@H]1[C@@]2(OC3=C([C@]1(C=4C(O2)=CC(O)=CC4O)[H])C5=C(C(O)=C3)C[C@H](O)[C@H](O5)C6=CC(O)=C(O)C=C6)C7=CC(O)=C(O)C=C7

Synonyms:

• (+)-Proanthocyanidin A1
• (+)-Proanthocyanidin A₁
• (2R,3S,8S,14R,15R)-2,8-Bis(3,4-dihydroxyphenyl)-3,4-dihydro-8,14-methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol
• 8,14-Methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol,2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-, [2R-(2a,3b,8b,14b,15R*)]-
• 8,14-Methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol, 2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R,3S,8S,14R,15R)-
• EPICATECHIN-(4BETA->8:2BETA-O-7) CATECHIN
• 2BETA-O-7) CATECHIN
• PROCYANIDIN A1
• EPICATECHIN-(4BETA->8

Procyanidin A1

CAS: 103883-03-0

Purity: 99.19%

Molecular weight: 576.51

Ref: 10-F979817

Procyanidin A1

CAS: 103883-03-0

Procyanidin A1

Purity: ≥98%

Molecular weight: 576.5g/mol

Ref: 54-BUP00651

Procyanidin A1

CAS: 103883-03-0

Formula: C₃₀H₂₄O₁₂

Purity: ≥ 98.0%

Color and Shape: Off-white powder

Molecular weight: 576.51

Ref: 7W-GY1319

Procyanidin A1

CAS: 103883-03-0

Procyanidin A1 is a procyanidin with a chemical structure similar to the common flavonoid. It has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Procyanidin A1 also has an ability to block LPS-stimulated production of TNF-α and IL-6 in RAW 264.7 cells, as well as up-regulate the expression of genes involved in fatty acid metabolism. The bioactive phenolic compounds found in procyanidin A1 are capable of inhibiting mitochondrial membrane potential, leading to apoptosis, and can induce activation of the transcription factor NF-κB (a-type). In addition, procyanidin A1 has been shown to inhibit the growth of basophilic leukemia cells through upregulation of Bcl2 protein expression.

Formula: C₃₀H₂₄O₁₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 576.5 g/mol

Ref: 3D-FP74517

Procyanidin A1

CAS: 103883-03-0

Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+.

Formula: C₃₀H₂₄O₁₂

Purity: 99.52%

Color and Shape: Solid

Molecular weight: 576.5

Ref: TM-TN1136

Procyanidin A1

CAS: 103883-03-0

Procyanidin A1 has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2⁺ influx from an internal store in RBL-2H3 cells. Procyanidin A1 shows a very high inhibition effect on LDL oxidation, with the IC50 value of 0.94 uM.

Formula: C₃₀H₂₄O₁₂

Purity: 95%~99%

Molecular weight: 576.51

Ref: BP-BP1832

Procyanidin A1

CAS: 103883-03-0

Procyanidin A1 analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₃₀H₂₄O₁₂

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 576.51

Ref: 11-0986

Procyanidin a1

CAS: 103883-03-0

Oxygen-heterocyclic compound

Formula: C₃₀H₂₄O₁₂

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 576.5

Ref: 5G-83897

Procyanidin A1

CAS: 103883-03-0

Formula: C₃₀H₂₄O₁₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 576.5044

Ref: IN-DA008S0D