CAS 103884-98-6

2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one

Description:

2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one, commonly referred to as a nucleoside analog, is characterized by its structural features that include a purine base and a sugar moiety. The presence of a 2-deoxy-2-fluoro-β-D-arabinofuranosyl group indicates that it is a modified sugar, which enhances its stability and bioactivity compared to natural nucleosides. This compound exhibits properties typical of nucleoside analogs, such as potential antiviral or anticancer activity, as it can interfere with nucleic acid synthesis. Its amino group at the 2-position of the purine ring contributes to its reactivity and interaction with biological targets. The fluorine substitution on the sugar enhances its metabolic stability, making it a subject of interest in medicinal chemistry. Overall, this compound's unique structural modifications position it as a valuable candidate for further research in therapeutic applications, particularly in the development of antiviral and anticancer agents.

Formula: C₁₀H₁₂FN₅O₄

InChI: InChI=1/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4+,6-,9?/m1/s1

InChI key: InChIKey=UXUZARPLRQRNNX-AYQXTPAHSA-N

SMILES: O=C1C2=C(N(C=N2)[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3F)NC(N)=N1

Synonyms:

• 2-Amino-9-(2-deoxy-2-fluoro-β-<span class="text-smallcaps">D</span>-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one
• 2-Amino-9-[(3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
• 2-amino-9-(2-deoxy-2-fluoro-D-arabinofuranosyl)-3,9-dihydro-6H-purin-6-one
• 6H-Purin-6-one, 2-amino-9-(2-deoxy-2-fluoro-β-<span class="text-smallcaps">D</span>-arabinofuranosyl)-1,9-dihydro-
• 6H-Purin-6-one, 2-amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-1,9-dihydro-
• 9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin
• Nuk-2
• 2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one
• 2′-Fluoro-Arabinoguanosine
• 2′-F-Ara-guanosine
• 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)guanine
• 9-(2-deoxy-2-fluoroarabinofuranosyl)guanine
• 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine
• 9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanine
• 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine
• 2’-Deoxy-2’-fluoro-β-D-arabinoguanosine
• 2'-Fluoro-2'-deoxy-arabinofuranosyl-guanosine
• 2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine

9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine

CAS: 103884-98-6

Formula: C₁₀H₁₂FN₅O₄

Purity: %

Color and Shape: Solid

Molecular weight: 285.2318

Ref: IN-DA008Z7H

2'-Deoxy-2'-fluoro-β-D-arabinoguanosine

CAS: 103884-98-6

2'-Deoxy-2'-fluoro-β-D-arabinoguanosine

Purity: ≥98%

Molecular weight: 285.23g/mol

Ref: 54-BUP05207

9-(2''-Deoxy-2''-fluoro-b-D-arabinofuranosyl)guanine

CAS: 103884-98-6

Ref: 7W-GN1343

2'-Deoxy-2'-fluoro-β-D-arabinoguanosine

CAS: 103884-98-6

2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert

Formula: C₁₀H₁₂FN₅O₄

Purity: 99.42%

Color and Shape: Solid

Molecular weight: 285.23

Ref: TM-TNU0168

9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)guanine

CAS: 103884-98-6

9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine is a nucleoside phosphorylase inhibitor that is used to treat inflammatory bowel disease. It has been shown to be effective in treating women with inflammatory bowel disease, and has no significant side effects. 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine inhibits the bacterial enzyme nucleoside phosphorylase, which is responsible for the conversion of guanosine triphosphate (GTP) to guanosine diphosphate (GDP). This inhibition prevents the synthesis of DNA and RNA by blocking the conversion of GTP and GDP into AMP and GMP. The drug binds to the active site of nucleoside phosphorylase, which is located in the bacterial cytoplasmic membrane. 9-(2'-Deoxy-2'-fluoro

Formula: C₁₀H₁₂FN₅O₄

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 285.24 g/mol

Ref: 3D-ND08478

9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine

Controlled Product

CAS: 103884-98-6

Formula: C₁₀H₁₂FN₅O₄

Color and Shape: Neat

Molecular weight: 285.232

Ref: TR-D239970

9-(2\'-Deoxy-2\'-fluoro-b-D-arabinofuranosyl)guanine

CAS: 103884-98-6

Formula: C₁₀H₁₂FN₅O₄

Molecular weight: 285.24

Ref: ST-EA-CP-F71013