CAS 103909-75-7

Maxacalcitol

Description:

Maxacalcitol, with the CAS number 103909-75-7, is a synthetic analog of calcitriol, which is the active form of vitamin D. It is primarily used in the treatment of conditions related to calcium metabolism, such as secondary hyperparathyroidism, particularly in patients with chronic kidney disease. Maxacalcitol functions by binding to vitamin D receptors, thereby promoting intestinal absorption of calcium and phosphate, and influencing bone metabolism. This compound exhibits a high affinity for the vitamin D receptor, which enhances its efficacy in regulating calcium homeostasis. Maxacalcitol is typically administered topically or systemically, depending on the therapeutic context. Its pharmacokinetics involve rapid absorption and metabolism, with a relatively short half-life. As with other vitamin D analogs, potential side effects may include hypercalcemia and hyperphosphatemia, necessitating careful monitoring of serum calcium and phosphate levels during treatment. Overall, Maxacalcitol represents a valuable therapeutic option in managing disorders associated with vitamin D deficiency and calcium imbalance.

Formula: C₂₆H₄₂O₄

InChI: InChI=1S/C26H42O4/c1-17-20(15-21(27)16-24(17)28)9-8-19-7-6-12-26(5)22(10-11-23(19)26)18(2)30-14-13-25(3,4)29/h8-9,18,21-24,27-29H,1,6-7,10-16H2,2-5H3/b19-8+,20-9-/t18-,21+,22+,23-,24-,26+/m0/s1

InChI key: InChIKey=DTXXSJZBSTYZKE-ZDQKKZTESA-N

SMILES: C[C@@]12[C@](\C(=C\C=C\3/C(=C)[C@@H](O)C[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](OCCC(C)(C)O)C)[H])[H]

Synonyms:

• (+)-(5Z,7E)-(1S,3R,20S)-20-(3-Hydroxy-3-methylbutyloxy)-9,10-secopregna-5,7,10(19)-triene-1,3-diol
• (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
• (1S,3R,5Z,7E,9xi,20S)-20-(3-hydroxy-3-methylbutoxy)-9,10-secopregna-5,7,10-triene-1,3-diol
• 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-
• 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-
• 1,3-Cyclohexanediol, 4-methylene-5-[2-[octahydro-1-[1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, [1S-[1α(R*),3aβ,4E(1S*,3R*,5Z),7aα]]-
• 1α,25-Dihydroxy-22-oxavitamin D₃
• 22-Oxa-1,25-dihydroxyvitamin D₃
• 22-Oxa-1α,25-dihydroxyvitamin D₃
• 22-Oxacalcitriol
• Mc 1275
• OCT (steroid)
• Oxarol
• Prezios

22-Oxacalcitriol

CAS: 103909-75-7

Formula: C₂₆H₄₂O₄

Purity: %

Color and Shape: Solid

Molecular weight: 418.6093

Ref: IN-DA00857B

22-Oxacalcitriol

CAS: 103909-75-7

Molecular weight: 418.61

Ref: 7W-GV8735

Maxacalcitol

CAS: 103909-75-7

Maxacalcitol

Purity: ≥98%

Molecular weight: 418.61g/mol

Ref: 54-BUP01846

Maxacalcitol

CAS: 103909-75-7

Formula: C₂₆H₄₂O₄

Molecular weight: 418.62

Ref: 4Z-M-113001

Maxacalcitol

CAS: 103909-75-7

Vitamin D3 analogue

Formula: C₂₆H₄₂O₄

Purity: Min. 95%

Molecular weight: 418.61 g/mol

Ref: 3D-FM158459

Maxacalcitol

CAS: 103909-75-7

Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue.

Formula: C₂₆H₄₂O₄

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 418.61

Ref: TM-T16015