CAS 104-32-5

propamidine

Description:

Propamidine, with the CAS number 104-32-5, is an organic compound that belongs to the class of amidines. It is characterized by the presence of an amidine functional group, which consists of a carbon atom double-bonded to a nitrogen atom and single-bonded to another nitrogen atom. Propamidine is typically encountered as a white crystalline solid and is soluble in water and various organic solvents. It exhibits antimicrobial properties, making it useful in pharmaceutical applications, particularly as an antiseptic and in the treatment of certain infections. The compound has a relatively low toxicity profile, but like many chemical substances, it should be handled with care to avoid potential adverse effects. Its chemical structure allows for interactions with biological systems, which is essential for its therapeutic efficacy. Overall, propamidine is notable for its medicinal applications and its role in the development of antimicrobial agents.

Formula: C₁₇H₂₀N₄O₂

InChI: InChI=1/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21)

InChI key: InChIKey=WTFXJFJYEJZMFO-UHFFFAOYSA-N

SMILES: O(CCCOC1=CC=C(C(=N)N)C=C1)C2=CC=C(C(=N)N)C=C2

Synonyms:

• 4,4'-[Propane-1,3-Diylbis(Oxy)]Dibenzenecarboximidamide
• 4,4-Trimethylenedioxydibenzamidine
• 4,4′-(Trimethylenedioxy)dibenzamidine
• 4,4′-[1,3-Propanediylbis(oxy)]bis[benzenecarboximidamide]
• Benzamidine, 4,4′-(trimethylenedioxy)di-
• Benzenecarboximidamide, 4,4′-[1,3-propanediylbis(oxy)]bis-
• M. & B. 782
• Panamidin
• p,p′-(Trimethylenedioxy)dibenzamidine
• Propamidine
• 4,4'-[1,3-Propanediylbis(oxy)]bis(benzenecarbimidamide)
• 4,4'-(1,3-Propanediylbis(oxy))bisbenzenecarboximidamide
• DAPP
• 4,4'-(1,3-Propanediyl)bis(oxy)bisbenzamidine
• 4,4'-[1,3-Propanediylbis(oxy)]dibenzenecarboximidamide

Propamidine

CAS: 104-32-5

Propamidine is a drug that is used to treat amoebiasis. It is also used to kill trophozoites and prevent the disease activity in patients with amoebiasis. Propamidine has been shown to have a synergistic effect when administered with sodium succinate and benzalkonium chloride. Propamidine has been reported as being effective against resistant mutants of Entamoeba histolytica, but not against other types of parasitic protozoa or bacteria. Propamidine has been shown to be an effective chemotherapy agent for the treatment of infectious diseases such as malaria, toxoplasmosis, and leishmaniasis, which are caused by protozoa. This drug inhibits the growth of bacteria by binding to dna duplexes and preventing them from separating during replication. Propamidine also prevents the synthesis of proteins by inhibiting protein synthesis in bacterial cells.

Formula: C₁₇H₂₀N₄O₂

Purity: Min. 75%

Color and Shape: Off-White Yellow Powder

Molecular weight: 312.37 g/mol

Ref: 3D-FP151543

Propamidine

CAS: 104-32-5

Propamidine acts as a covalent inhibitor of TMPRSS2 and exhibits antibacterial properties. [1]

Formula: C₁₇H₂₀N₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 312.37

Ref: TM-T78610