CAS 104004-92-4

DIDESMETHYL MIFEPRISTONE

Description:

Didesmethyl mifepristone, identified by its CAS number 104004-92-4, is a synthetic compound related to mifepristone, a well-known antiprogestin used primarily in medical abortion and for the treatment of certain conditions like Cushing's syndrome. This substance is characterized by its structural modifications that result in the absence of two methyl groups compared to its parent compound. As a result, didesmethyl mifepristone exhibits altered pharmacological properties, potentially influencing its binding affinity to progesterone receptors. The compound is typically studied for its biological activity, including its effects on reproductive health and its potential therapeutic applications. In terms of physical properties, detailed data on solubility, stability, and reactivity may vary, but like many synthetic organic compounds, it is likely to be lipophilic. Safety and handling precautions are essential, as with any chemical substance, due to potential biological effects. Research into didesmethyl mifepristone continues to explore its efficacy and safety profile in various medical contexts.

Formula: C₂₇H₃₁NO₂

InChI: InChI=1/C27H31NO2/c1-3-13-27(30)14-12-24-22-10-6-18-15-20(29)9-11-21(18)25(22)23(16-26(24,27)2)17-4-7-19(28)8-5-17/h4-5,7-8,15,22-24,30H,6,9-12,14,16,28H2,1-2H3/t22-,23+,24-,26-,27?/m0/s1

Synonyms:

• Ru 42848
• (11,17)-11-(4-Aminophenyl)-17-hydroxy-17-(1-propyn-1-yl)-estra-4,9-dien-3-one
• Didemethyl Mifepristone
• N-Didesmethyl Mifepristone
• (11Beta)-11-(4-Aminophenyl)-17-Hydroxy-17-(Prop-1-Yn-1-Yl)Estra-4,9-Dien-3-One

N,N-Didesmethyl Mifepristone-d4

CAS: 104004-92-4

Formula: C₂₇H₂₇D₄NO₂

Color and Shape: Yellow Brown Solid

Molecular weight: 405.57

Ref: 4Z-M-299

N,N-Didesmethyl Mifepristone

CAS: 104004-92-4

Formula: C₂₇H₃₁NO₂

Color and Shape: Yellow Brown Solid

Molecular weight: 401.55

Ref: 4Z-M-294

Didemethyl Mifepristone

Controlled Product

CAS: 104004-92-4

Applications A metabolite of Mifepristone.
References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),

Formula: C₂₇H₃₁NO₂

Color and Shape: Neat

Molecular weight: 401.54

Ref: TR-D439550

Didemethyl mifepristone

Controlled Product

CAS: 104004-92-4

Didemethyl mifepristone is a synthetic glucocorticoid that has been shown to have a high affinity for the glucocorticoid receptor. It has been found to decrease insulin sensitivity and cortisol levels in healthy volunteers. The effects of didemethyl mifepristone on cortisol levels may be due to its ability to block the glucocorticoid receptor, thereby preventing the binding of cortisol to this receptor. This drug also blocks various receptors, such as mineralocorticoid and progesterone receptors. It is not known if didemethyl mifepristone is an antagonist for other receptors or not.

Formula: C₂₇H₃₁NO₂

Purity: Min. 95%

Molecular weight: 401.54 g/mol

Ref: 3D-FD21732

N-Didesmethyl Mifepristone

CAS: 104004-92-4

Formula: C₂₇H₃₁NO₂

Molecular weight: 401.6

Ref: ST-EA-CP-M61008