CAS 104010-37-9

Ceftiofur sodium

Description:

Ceftiofur sodium is a broad-spectrum cephalosporin antibiotic primarily used in veterinary medicine. It is effective against a variety of Gram-positive and Gram-negative bacteria, making it valuable for treating infections in livestock and poultry. The compound is characterized by its ability to inhibit bacterial cell wall synthesis, which is a common mechanism of action for beta-lactam antibiotics. Ceftiofur sodium is typically administered via injection and is known for its relatively low toxicity in animals. It is often used to treat respiratory diseases, mastitis, and other bacterial infections in cattle, swine, and poultry. The sodium salt form enhances its solubility and stability, facilitating its use in clinical settings. Additionally, ceftiofur has a withdrawal period, which is the time required for the drug to clear from the animal's system before slaughter, ensuring that antibiotic residues do not enter the food supply. Overall, ceftiofur sodium plays a significant role in veterinary therapeutics, contributing to animal health and productivity.

Formula: C₁₉H₁₇N₅O₇S₃·Na

InChI: InChI=1S/C19H17N5O7S3.Na/c1-30-23-11(9-7-34-19(20)21-9)14(25)22-12-15(26)24-13(17(27)28)8(5-32-16(12)24)6-33-18(29)10-3-2-4-31-10;/h2-4,7,12,16H,5-6H2,1H3,(H2,20,21)(H,22,25)(H,27,28);/b23-11-;/t12-,16-;/m1./s1

InChI key: InChIKey=DJTLOEQCWGUKEM-JUODUXDSSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1CSC(=O)C4=CC=CO4)[H].[Na]

Synonyms:

• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-, monosodium salt, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-, monosodium salt, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-, sodium salt (1:1), (6R,7R)-
• Ceftiofur Sodium Salt
• Ceftiofur sodium
• Excenell
• Naxcel
• U-64279E
• Xceft
• sodium (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• sodium 7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Ceftiofur sodium, 95%

CAS: 104010-37-9

A broad spectrum antibiotic

Formula: C₁₉H₁₆N₅NaO₇S₃

Purity: 95%

Molecular weight: 545.54

Ref: 02-J66886

Ceftiofur sodium

CAS: 104010-37-9

Formula: C₁₉H₁₆N₅NaO₇S₃

Purity: 85%

Color and Shape: Solid

Molecular weight: 545.5444

Ref: IN-DA00855T

Ceftiofur sodium

CAS: 104010-37-9

Ceftiofur sodium (Naxcel), an antibiotic of the cephalosporin type (third generation), is used as veterinary medicine.

Formula: C₁₉H₁₆N₅NaO₇S₃

Purity: 97.71% - 99.36%

Color and Shape: Off-White Or Yellowish Crystalline Powder

Molecular weight: 545.54

Ref: TM-T0198

Ceftiofur sodium

CAS: 104010-37-9

Ceftiofur sodium

Formula: C₁₉H₁₆N₅O₇S₃Na

Purity: ≥95%

Color and Shape: cream solid

Molecular weight: 545.553g/mol

Ref: 54-OR902510

Ceftiofur-d3 Sodium Salt

CAS: 104010-37-9

Formula: C₁₉H₁₃D₃N₅O₇S₃·Na

Color and Shape: White To Off-White Solid

Molecular weight: 525.56 22.99

Ref: 4Z-C-862

Ceftiofur sodium

CAS: 104010-37-9

Ceftiofur sodium

Purity: ≥95%

Molecular weight: 545.54g/mol

Ref: 54-BUP14838

Ceftiofur sodium salt

CAS: 104010-37-9

Formula: C₁₉H₁₆N₅O₇S₃·Na·xH₂O

Purity: ≥ 85.0% (C20H19N5O7S3, dried basis)

Color and Shape: White, off-white or light-yellow powder

Molecular weight: 545.54 (anhydrous)

Ref: 7W-GA9758

Ceftiofur Sodium

CAS: 104010-37-9

Applications Ceftiofur Sodium is a cephalosporin based antibacterial compound.
References Heinrich, K. et al: Food Addit. Contam. A., 30, 1733 (2013); Harlow, B. et al.: Veter. Microbiol., 166, 225 (2013);

Formula: C₁₉H₁₆N₅O₇S₃·Na

Color and Shape: Neat

Molecular weight: 545.54

Ref: TR-C244740

Ceftiofur sodium

CAS: 104010-37-9

Ceftiofur sodium is a veterinary antibiotic that belongs to the class of antimicrobial agents. It is the most active agent for treating infections caused by gram-positive bacteria and has been shown to have a high degree of efficacy against amoxicillin-clavulanic acid-resistant strains. Ceftiofur sodium binds to bacterial ribosomes and inhibits protein synthesis, leading to cell death by inhibiting proteins vital for cell division. Ceftiofur sodium also inhibits DNA synthesis by binding to DNA gyrase, which is an enzyme that maintains the integrity of bacterial DNA. Ceftiofur hydrochloride (CFT) is a prodrug that is hydrolyzed in vivo to ceftiofur sodium, its active form. Ceftiofur hydrochloride has been shown to be effective against tetracycline-resistant Staphylococcus aureus (TETR) and Mycobacterium tuberculosis complex, but not against Escherichia

Formula: C₁₉H₁₆N₅NaO₇S₃

Purity: Min. 95 Area-%

Color and Shape: Off-White Powder

Molecular weight: 545.55 g/mol

Ref: 3D-FC37914

Ceftiofur sodium salt

CAS: 104010-37-9

Formula: C₁₉H₁₆N₅NaO₇S₃

Purity: 85%

Color and Shape: Solid, Powder

Molecular weight: 545.53

Ref: 10-F361965