CAS 10405-02-4

Trospium chloride

Description:

Trospium chloride is a synthetic quaternary ammonium compound primarily used as an antimuscarinic agent for the treatment of overactive bladder. It functions by inhibiting the action of acetylcholine on muscarinic receptors in the bladder, thereby reducing involuntary contractions and increasing bladder capacity. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Trospium chloride has a relatively low bioavailability due to its quaternary structure, which limits its ability to cross the blood-brain barrier, thus minimizing central nervous system side effects. Its pharmacokinetics are characterized by a rapid onset of action, with peak plasma concentrations typically occurring within a few hours after oral administration. Common side effects may include dry mouth, constipation, and urinary retention. As with any medication, it is essential to consider contraindications and potential interactions with other drugs. Overall, Trospium chloride is an effective option for managing symptoms associated with overactive bladder while maintaining a favorable safety profile.

Formula: C₂₅H₃₀NO₃·Cl

InChI: InChI=1/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1/t21-,22+,23+;

InChI key: InChIKey=RVCSYOQWLPPAOA-QKYUOBHYNA-M

SMILES: O(C(C(O)(C1=CC=CC=C1)C2=CC=CC=C2)=O)[C@@H]3C[C@]4([N+]5([C@@](C3)(CC4)[H])CCCC5)[H].[Cl-]

Synonyms:

• As XVII
• Azoniaspiro compound XVII
• Azoniaspiro(3α-benziloyloxynortropane-8,1'-pyrrolidine) chloride
• Benzilic acid, ester with 3α-hydroxyspiro[1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-nortropane-8,1′-pyrrolidinium] chloride
• Chlorure De Trospium
• Cloruro De Trospio
• Keptan
• Relaspium
• Sanctura
• Sanctura XR
• Spasmex
• Spasmo 3
• Spasmo-lyt
• Spiro[1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-nortropane-8,1′-pyrrolidinium], 3α-hydroxy-, chloride, benzilate
• Spiro[1αH,5αH-nortropane-8,1'-pyrrolidinium], 3α-hydroxy-, chloride, benzilate
• Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium], 3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-, chloride (1:1), (1α,3β,5α)-
• Tar 302-5018
• Trospium Chloride
• Trospiumchlorid
• Trozyd
• Spiro[8-azoniabicyclo[3.2.1]octane-8,1′-pyrrolidinium], 3-[(hydroxydiphenylacetyl)oxy]-, chloride, (1α,3β,5α)-

Trospium Chloride

CAS: 10405-02-4, 47608-32-2

Formula: C₂₅H₃₀ClNO₃

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 427.97

Ref: 3B-T3305

TROSPIUM CHLORIDE CRS

CAS: 10405-02-4

TROSPIUM CHLORIDE CRS

Formula: C₂₅H₃₀NO₃

Color and Shape: Powder

Molecular weight: 392.5101

Ref: 41-Y0000429

Trospium chloride impurity standard

CAS: 10405-02-4, 16444-19-2, 76-93-7

Trospium chloride impurity standard

Color and Shape: Off White Solid

Ref: 47-1155

Trospium chloride

CAS: 10405-02-4

Trospium chloride

Formula: C₂₅H₃₀ClNO₃

Purity: 99.5%

Color and Shape: Off-White

Molecular weight: 427.19142

Ref: 47-1064

Trospium Chloride

CAS: 10405-02-4

Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoi

Formula: C₂₅H₃₀ClNO₃

Color and Shape: White Light Yellow Powder

Molecular weight: 427.19142

Ref: 45-1699300

TROSPIUM CHLORIDE

CAS: 10405-02-4

Formula: C₂₅H₃₀ClNO₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 427.9636

Ref: IN-DA007F2F

Trospium chloride

CAS: 10405-02-4

Trospium chloride treats urinary incontinence without causing liver damage.

Formula: C₂₅H₃₀ClNO₃

Purity: 99.84% - >99.99%

Color and Shape: White To Off-White Powder

Molecular weight: 427.964

Ref: TM-T1472

Trospium Chloride

CAS: 10405-02-4

Formula: C₂₅H₃₀NO₃·Cl

Color and Shape: White To Off-White Solid

Molecular weight: 392.52 35.45

Ref: 4Z-T-222

Trospium chloride

CAS: 10405-02-4

Trospium chloride

Purity: ≥98%

Molecular weight: 427.964g/mol

Ref: 54-BUP16921

Trospium chloride

CAS: 10405-02-4

Ref: 7W-GK2146

Trospium-d8 Chloride

CAS: 10405-02-4

Formula: C₂₅H₂₂D₈NO₃·Cl

Color and Shape: White To Off-White Solid

Molecular weight: 400.57 35.45

Ref: 4Z-T-221

Trospium Chloride

CAS: 10405-02-4

Trospium Chloride

Purity: 99%

Molecular weight: 427.96g/mol

Ref: 54-OR1028853

Trospium Chloride

CAS: 10405-02-4

Color and Shape: Neat

Ref: 61-FOR1266.00

Trospium Chloride

Controlled Product

CAS: 10405-02-4

Formula: C₂₅H₃₀NO₃·Cl

Color and Shape: Neat

Molecular weight: 427.96

Ref: 86-MM1266.00

Trospium Chloride

Controlled Product

CAS: 10405-02-4

Applications Tropine derivative with anticholinergic activity. Antispasmodic; used in treatment of urinary incontinence.
References Antweiler, H., et al.: Arzneim.-Forsch., 16, 1581 (1966), Lux, G., et al.: Fortschr. Med., 96, 2113 (1978), Madersbacher, H., et al.: Br. J. Urol., 75, 452 (1995), Zinner, N.R., et al.: Expert Opin. Pharmacother., 6, 1409 (2005),

Formula: C₂₅H₃₀NO₃·Cl

Color and Shape: Neat

Molecular weight: 427.96

Ref: TR-T892800

Trospium-d8 Chloride

Controlled Product

CAS: 10405-02-4

Applications Tropine derivative with anticholinergic activity. Antispasmodic; used in treatment of urinary incontinence.
References Antweiler, H., et al.: Arzneim.-Forsch., 16, 1581 (1966), Lux, G., et al.: Fortschr. Med., 96, 2113 (1978), Madersbacher, H., et al.: Br. J. Urol., 75, 452 (1995), Zinner, N.R., et al.: Expert Opin. Pharmacother., 6, 1409 (2005),

Formula: C₂₅H₂₂D₈ClNO₃

Color and Shape: Neat

Molecular weight: 436.01

Ref: TR-T892802