(D-Phe2)-VIP, also known as vasoactive intestinal peptide, is a synthetic analog of the naturally occurring vasoactive intestinal peptide (VIP) that has been modified to enhance its stability and receptor affinity. This peptide is characterized by the substitution of the second phenylalanine residue with D-phenylalanine, which contributes to its resistance to enzymatic degradation. It exhibits potent vasodilatory effects and plays a significant role in various physiological processes, including smooth muscle relaxation, stimulation of glandular secretion, and modulation of immune responses. (D-Phe2)-VIP interacts with specific VIP receptors, leading to a cascade of intracellular signaling pathways that influence cellular functions. Its applications extend to research in neurobiology, gastrointestinal physiology, and potential therapeutic uses in conditions such as asthma, inflammatory bowel disease, and other disorders where modulation of vascular and immune responses is beneficial. The CAS number 104051-15-2 uniquely identifies this compound, facilitating its recognition in scientific literature and databases.

(D-Phe2)-VIP (human, bovine, porcine, rat)

104051-15-2: (D-Phe2)-VIP, also known as vasoactive intestinal peptide, is a synthetic analog of the naturally occurring vasoactive intestinal peptide (VIP) that has been modified to enhance its stability and receptor affinity. This peptide is characterized by the substitution of the second phenylalanine residue with D-phenylalanine, which contributes to its resistance to enzymatic degradation. It exhibits potent vasodilatory effects and plays a significant role in various physiological processes, including smooth muscle relaxation, stimulation of glandular secretion, and modulation of immune responses. (D-Phe2)-VIP interacts with specific VIP receptors, leading to a cascade of intracellular signaling pathways that influence cellular functions. Its applications extend to research in neurobiology, gastrointestinal physiology, and potential therapeutic uses in conditions such as asthma, inflammatory bowel disease, and other disorders where modulation of vascular and immune responses is beneficial. The CAS number 104051-15-2 uniquely identifies this compound, facilitating its recognition in scientific literature and databases.

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CAS 104051-15-2

(D-Phe2)-VIP (human, bovine, porcine, rat)

(D-Phe2)-VIP (human, mouse, rat)

Ref: 3D-FP109564