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CAS 104076-39-3

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Zolantidine dimaleate

Description:
Zolantidine dimaleate is a chemical compound primarily recognized for its role as an antihistamine, particularly in the treatment of allergic conditions. It functions as a selective H2 receptor antagonist, which means it inhibits the action of histamine at the H2 receptor sites, thereby reducing gastric acid secretion and alleviating symptoms associated with conditions like peptic ulcers and gastroesophageal reflux disease (GERD). The compound is typically presented as a dimaleate salt, enhancing its solubility and stability. Zolantidine dimaleate exhibits a favorable pharmacokinetic profile, allowing for effective absorption and distribution in the body. Its safety and efficacy have been evaluated in clinical settings, contributing to its therapeutic applications. As with many pharmaceuticals, potential side effects may include dizziness, headache, or gastrointestinal disturbances, although these are generally mild. Overall, Zolantidine dimaleate represents a significant advancement in the management of histamine-related disorders, showcasing the importance of H2 receptor antagonists in modern medicine.
Formula:C22H27N3OS·2C4H4O4
InChI:InChI=1S/C22H27N3OS.C4H4O4/c1-4-13-25(14-5-1)17-18-8-6-9-19(16-18)26-15-7-12-23-22-24-20-10-2-3-11-21(20)27-22;5-3(6)1-2-4(7)8/h2-3,6,8-11,16H,1,4-5,7,12-15,17H2,(H,23,24);1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key:InChIKey=ZKHYAKSUYKITHP-BTJKTKAUSA-N
SMILES:N(CCCOC1=CC(CN2CCCCC2)=CC=C1)C3=NC=4C(S3)=CC=CC4.C(=C\C(O)=O)\C(O)=O
Synonyms:
  • 2-Benzothiazolamine, N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-, (2Z)-2-butenedioate (1:2)
  • 2-Benzothiazolamine, N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-, (Z)-2-butenedioate (1:2)
  • Zolantidine dimaleate
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