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CAS 104090-92-8

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FMOC-GLU(OBUT)-NH2

Description:
FMOC-GLU(OBUT)-NH2, also known as Fmoc-Glutamic acid (OBuT), is a protected amino acid commonly used in peptide synthesis. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during the synthesis process. The "GLU" indicates that the molecule contains glutamic acid, an important amino acid involved in protein synthesis and metabolism. The "OBUT" refers to a butyl ester protecting group on the carboxylic acid side of the glutamic acid, which helps to prevent unwanted reactions during peptide coupling. This compound is typically used in solid-phase peptide synthesis, where the protection and deprotection of functional groups are crucial for the successful assembly of peptides. Its stability under various conditions and compatibility with standard coupling reagents make it a valuable building block in the field of organic and medicinal chemistry. Additionally, FMOC-GLU(OBUT)-NH2 is utilized in research and development for synthesizing bioactive peptides and studying protein interactions.
Formula:C24H28N2O5
Synonyms:
  • Fmoc-L-Glutamic Acid Gamma-T-Butyl Ester Alpha-Amide
  • Fmoc-Isogln(But)-Oh
  • Fmoc-L-Glu(tBu)-NH2
  • Fmoc-L-IsoGln-OtBu, N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-isoglutamine t-butyl ester, N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-glutamic-acid alpha-amide gamma t-butyl ester
  • Fmoc-L-glutamic acid -t-butyl ester -amide
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