CAS 104091-08-9

Fmoc-D-Glu(OtBu)-OH

Description:

Fmoc-D-Glu(OtBu)-OH, also known as Fmoc-D-glutamic acid tert-butyl ester, is a protected form of the amino acid glutamic acid. It features a fluorenylmethoxycarbonyl (Fmoc) group, which is commonly used in peptide synthesis to protect the amino group, allowing for selective reactions at the carboxyl group. The tert-butyl ester (OtBu) protects the carboxylic acid functionality, enhancing the stability and solubility of the compound. This substance is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. It is widely utilized in the field of organic chemistry and peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), due to its ability to facilitate the sequential addition of amino acids while preventing unwanted side reactions. The compound's stability under various conditions makes it a valuable intermediate in the synthesis of peptides and other bioactive molecules.

Formula: C₂₄H₂₇NO₆

InChI: InChI=1/C24H27NO6/c1-24(2,3)31-21(26)13-12-20(22(27)28)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,27,28)/t20-/m1/s1

SMILES: CC(C)(C)OC(=O)CC[C@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12

Synonyms:

• Fmoc-D-Glu(OBut)-OH
• N-alpha-(9-fluorenylmethyloxycarbonyl)-D-glutamic-acid-gamma-t-butyl ester
• Fmoc-D-glutamic acid gamma-tert-butyl ester
• Quinoline-6-Carbaldehyde
• (2R)-5-tert-butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
• Fmoc-D-glutamic acid 5-tert-butyl ester
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-GLUTAMIC ACID GAMMA-T-BUTYL ESTER
• FMOC-D-GLU(OBUT) H2O
• FMOC-D-GLU(OTBU)-OH
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-GLUTAMIC-ACID-GAMMA-TERT-BUTYL ESTER MONOHYDRATE
• n-(9-fluorenylmethoxycarbonyl)-d-glutamic acid gamma-tert-butyl ester
• FMOC-D-GLU(TBU)-OH
• 9-FLUORENYLMETHOXYCARBONYL-D-GLUTAMIC ACID GAMMA-T-BUTYL ESTER MONOHYDRATE
• N-ALPHA-FMOC-D-GLUTAMIC ACID GAMMA-TERT-BUTYL ESTER
• FMOC-D-GLUTAMIC ACID(OTBU)-OH
• N-ALPHA-FMOC-D-GLUTAMIC ACID GAMMA-T-BUTYL ESTER
• FMOC-D-GLU(OTBU)-OH H2O
• FMOC-D-GLUTAMIC ACID(O-T-BUTYL)
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-GLUTAMIC ACID GAMMA-T-BUTYL ESTER MONOHYDRATE
• FMOC-D-GLUTAMIC ACID GAMMA-T-BUTYL ESTER
• FMOC-D-GLU(TBU)-OH H2O

N-Fmoc-D-glutamic acid 5-tert-butyl ester, 98%

CAS: 104091-08-9

It is an important raw material and intermediate used in organic synthesis, agrochemicals and dyestuff. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Ae

Formula: C₂₄H₂₇NO₆

Purity: 98%

Molecular weight: 425.48

Ref: 02-H66624

Fmoc-D-Glu(OtBu)-OH · H₂O

CAS: 104091-08-9

Bachem ID: 4004498.

Formula: C₂₄H₂₇NO₆·H₂O

Purity: 99.7%

Color and Shape: White

Molecular weight: 443.5

Ref: 01-4004498

D-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-,5-(1,1-dimethylethyl) ester

CAS: 104091-08-9

Formula: C₂₄H₂₇NO₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 425.4743

Ref: IN-DA00HAA5

FMOC-D-Glu(OtBu)-OH

CAS: 104091-08-9

FMOC-D-Glu(OtBu)-OH

Formula: C₂₄H₂₇NO₆

Purity: 98%

Color and Shape: white solid

Molecular weight: 425.47g/mol

Ref: 54-OR960642

5-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-glutamate

CAS: 104091-08-9

Formula: C₂₄H₂₇NO₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 425.48

Ref: 3B-B3669

Fmoc-D-Glu(OtBu)-OH

CAS: 104091-08-9

Formula: C₂₄H₂₇NO₆

Purity: ≥ 98.0%

Color and Shape: White to almost white powder or crystals

Molecular weight: 425.47

Ref: 7W-GM7634

Fmoc-D-Glu(OtBu)-OH

CAS: 104091-08-9

Fmoc-D-Glu(OtBu)-OH is an amino acid that is used in peptide synthesis. It can be used as a building block or as a tool for peptide synthesis. Fmoc-D-Glu(OtBu)-OH has the following characteristics:

Formula: C₂₄H₂₇NO₆

Purity: Min. 95%

Molecular weight: 425.49 g/mol

Ref: 3D-FDE-1810-PI

Fmoc-D-Glu(OtBu)-OH.H2O

CAS: 104091-08-9

M03413 - Fmoc-D-Glu(OtBu)-OH.H2O

Formula: C₂₄H₂₇NO₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 425.481

Ref: 10-M03413

FMOC-D-Glutamic Acid 5-Tert-Butyl Ester (FMOC-D-Glu(OtBu)-OH) extrapure, 99%

CAS: 104091-08-9

Formula: C₂₄H₂₇NO₆

Purity: min. 99%

Color and Shape: White, Powder

Molecular weight: 425.47

Ref: SR-21323

Fmoc-D-Glu(OtBu)-OH

CAS: 104091-08-9

Fmoc-D-glu(OtBu)-OH is a homologous molecule that binds to the influenza virus and inhibits its replication. The synthesis of Fmoc-D-glu(OtBu)-OH is achieved by solid-phase peptide synthesis, which involves the ligation of amino acid building blocks on an insoluble carrier resin. This process has been found to be effective for the synthesis of peptides with a variety of amino acid sequences. Fmoc-D-glu(OtBu)-OH has been shown to inhibit the growth and multiplication of Chlorella pyrenoidosa, a single celled green alga, and Paramecium tetraurelia, a protozoan ciliate. It also displays antimycobacterial activity against Mycobacterium tuberculosis in vitro.

Formula: C₂₄H₂₇NO₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 425.47 g/mol

Ref: 3D-FF39368