CAS 1041-01-6

Diiodothyronine

Description:

Diiodothyronine, also known as 3,3'-diiodothyronine (3,3'-T2), is a thyroid hormone derivative that plays a role in regulating metabolism and energy homeostasis in the body. It is characterized by the presence of two iodine atoms attached to the phenolic rings of the thyronine structure, which is crucial for its biological activity. Diiodothyronine is less biologically active than its more well-known counterparts, thyroxine (T4) and triiodothyronine (T3), but it still contributes to metabolic processes. The compound is typically found in trace amounts in the bloodstream and is produced through the deiodination of T4 and T3. Its effects include modulation of gene expression and influence on cellular metabolism. Diiodothyronine is also of interest in research related to thyroid function and disorders, as well as its potential implications in metabolic diseases. The CAS number 1041-01-6 uniquely identifies this compound in chemical databases, facilitating its study and application in various scientific fields.

Formula: C₁₅H₁₃I₂NO₄

InChI: InChI=1S/C15H13I2NO4/c16-11-5-8(7-13(18)15(20)21)6-12(17)14(11)22-10-3-1-9(19)2-4-10/h1-6,13,19H,7,18H2,(H,20,21)/t13-/m0/s1

InChI key: InChIKey=ZHSOTLOTTDYIIK-ZDUSSCGKSA-N

SMILES: O(C1=C(I)C=C(C[C@@H](C(O)=O)N)C=C1I)C2=CC=C(O)C=C2

Synonyms:

• (2S)-2-Amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid
• (2S)-2-amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodo-phenyl]propanoic acid
• 3,5-Diiodi-L-thyronine
• 3,5-Diiodo-4-(4-Hydroxyphenoxy)-L-Phenylalanine
• 3,5-Diiodo-<span class="text-smallcaps">L</span>-thyronine
• 3,5-Diiodo-L-thyronine = 3,5-Diiodo-L-thyronine
• 3,5-Diiodothyronine
• 3-5-diiodo-L-thyronine crystalline
• 3-[4-p-[Hydroxyphenoxy]-3,5-diiodophenyl] alanine
• <span class="text-smallcaps">L</span>-3,5-Diiodothyronine
• <span class="text-smallcaps">L</span>-Diiodothyronine
• <span class="text-smallcaps">L</span>-T₂
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxyphenyl)-3,5-diiodo-
• Alanine, 3-[4-(p-hydroxyphenoxy)-3,5-diiodophenyl]-, <span class="text-smallcaps">L</span>-
• Diiodo-<span class="text-smallcaps">L</span>-thyronine
• Diiodothyronine
• L-Tyrosine, O-(4-Hydroxyphenyl)-3,5-Diiodo-
• NSC 90469
• O-(4-Hydroxyphenyl)-3,5-Diiodo-L-Tyrosine
• O-(4-Hydroxyphenyl)-3,5-diiodo-<span class="text-smallcaps">L</span>-tyrosine
• O-(4-hydroxyphenyl)-3,5-diiodotyrosine
• Alanine, 3-[4-(p-hydroxyphenoxy)-3,5-diiodophenyl]-, L-

3,5-Diiodo-L-thyronine

CAS: 1041-01-6

Formula: C₁₅H₁₃I₂NO₄

Purity: >96.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 525.08

Ref: 3B-D1119

Diiodothyronine (O-(4-Hydroxylphenyl)-3,5-diiodo-L-tyrosine)

CAS: 1041-01-6

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₁₅H₁₃I₂NO₄

Color and Shape: Off-White Light Yellow Powder

Molecular weight: 524.8934

Ref: 45-1204339

3,5-Diiodo-L-thyronine

CAS: 1041-01-6

Formula: C₁₅H₁₃I₂NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 525.0770

Ref: IN-DA003INK

3,5-Diiodo-L-thyronine

CAS: 1041-01-6

3,5-Diiodo-L-thyronine

Purity: ≥98%

Molecular weight: 525.08g/mol

Ref: 54-BUP17466

3,5-Diiodo-L-thyronine

CAS: 1041-01-6

3,5-Diiodo-L-thyronine

Purity: 97%

Molecular weight: 525.08g/mol

Ref: 54-OR1027140

Liothyronine EP Impurity E (Levothyroxine EP Impurity E)

CAS: 1041-01-6

Formula: C₁₅H₁₃I₂NO₄

Color and Shape: Pale Brown Solid

Molecular weight: 525.08

Ref: 4Z-T-4213

(2S)-2-Amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic Acid (Diiodothyronine)

Controlled Product

CAS: 1041-01-6

Formula: C₁₅H₁₃I₂NO₄

Color and Shape: Neat

Molecular weight: 525.08

Ref: 86-MM0626.08

3,5-Diiodo-L-thyronine

CAS: 1041-01-6

Formula: C₁₅H₁₃I₂NO₄

Purity: ≥ 97.0% (dried basis)

Color and Shape: White to off-white or faint yellow powder or crystals

Molecular weight: 525.08

Ref: 7W-GM6754

3,5-Diiodo-L-thyronine

CAS: 1041-01-6

NSC 90469 (Diiodothyronine) is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis and insulin resistance.

Formula: C₁₅H₁₃I₂NO₄

Purity: 99.64%

Color and Shape: Off-White Solid

Molecular weight: 525.08

Ref: TM-T4461

3,5-Diiodo-L-thyronine

CAS: 1041-01-6

Formula: C₁₅H₁₃I₂NO₄

Color and Shape: White To Light Beige

Molecular weight: 525.08

Ref: TR-D455155

3,5-Diiodo-L-thyronine

CAS: 1041-01-6

3,5-Diiodo-L-thyronine (3,5DIT) is a thyroid hormone that has been shown to have a number of physiological effects. It is capable of altering the activity of target enzymes, such as growth factor β1 and 3,5-diiodo-L-thyronine 5'-deiodinase (DID). 3,5DIT can stimulate cardiac effects by binding to the nuclear receptor TRβ1. It also stimulates weight loss by regulating fat metabolism through its effect on adipose tissue. 3,5DIT has been shown to alter mitochondrial functions and mitochondrial energy metabolism. This hormone may be used as an analytical tool for measuring mitochondrial functions in living cells.

Formula: C₁₅H₁₃I₂NO₄

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 525.08 g/mol

Ref: 3D-FD03332

3,5-Diiodo-L-thyronine

CAS: 1041-01-6

Formula: C₁₅H₁₃I₂NO₄

Purity: 95%

Color and Shape: White – Very pale reddish yellow powder

Molecular weight: 525.081

Ref: 10-F049610

3,5-Diiodo-L-thyronine (4-Hydroxyphenyl-13C6) Hydrochloride

Controlled Product

CAS: 1041-01-6

Applications 3,5-Diiodo-L-thyronine (4-Hydroxyphenyl-13C6) Hydrochloride is an isotopic analog of 3,5-Diiodo-L-thyronine (D455155), an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance.
References Huang, C.J., et al.: J. Mol. Cell. Cardiol., 31, 881-93 (1999);

Formula: C₉₁₃C₆H₁₃I₂NO₄(HCl)

Color and Shape: Neat

Molecular weight: 567.49

Ref: TR-D455164

Liothyronine EP Impurity E

CAS: 1041-01-6

Formula: C₁₅H₁₃I₂NO₄

Molecular weight: 525.08

Ref: ST-EA-CP-L45005

Levothyroxine EP Impurity E

CAS: 1041-01-6

Formula: C₁₅H₁₃I₂NO₄

Molecular weight: 525.08

Ref: ST-EA-CP-L18005