CAS 104145-95-1

Cefditoren

Description:

Cefditoren is a broad-spectrum cephalosporin antibiotic that is primarily used to treat bacterial infections. It is characterized by its ability to inhibit bacterial cell wall synthesis, which is a common mechanism of action among beta-lactam antibiotics. Cefditoren is effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating respiratory tract infections, skin infections, and other bacterial diseases. The compound is typically administered orally and is known for its favorable pharmacokinetic properties, including good absorption and distribution in the body. Its chemical structure features a beta-lactam ring, which is essential for its antibacterial activity, and it is often formulated as the prodrug cefditoren pivoxil to enhance its bioavailability. As with other antibiotics, the use of cefditoren should be guided by susceptibility testing to avoid the development of antibiotic resistance. Potential side effects may include gastrointestinal disturbances and allergic reactions, similar to those seen with other cephalosporins.

Formula: C₁₉H₁₈N₆O₅S₃

InChI: InChI=1S/C19H18N6O5S3/c1-8-11(33-7-21-8)4-3-9-5-31-17-13(16(27)25(17)14(9)18(28)29)23-15(26)12(24-30-2)10-6-32-19(20)22-10/h3-4,6-7,13,17H,5H2,1-2H3,(H2,20,22)(H,23,26)(H,28,29)/b4-3-,24-12-/t13-,17-/m1/s1

InChI key: InChIKey=KMIPKYQIOVAHOP-YLGJWRNMSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1/C=C\C4=C(C)N=CS4)[H]

Synonyms:

• (6R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, [6R-[3(Z),6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, (6R,7R)-
• Cefditoren acid
• Cefditoren main-ring
• Cefditoren

Cefditoren

CAS: 104145-95-1

Formula: C₁₉H₁₈N₆O₅S₃

Color and Shape: Pale Yellow Solid

Molecular weight: 506.57

Ref: 4Z-C-7612

Cefditoren Impurity 16

CAS: 104145-95-1, 2747915-67-7

Formula: C₃₃H₃₆N₆O₈S₃

Color and Shape: Pale Yellow Solid

Molecular weight: 740.87

Ref: 4Z-C-7622