CAS 10416-58-7

N,N-Bis(trimethylsilyl)acetamide

Description:

N,N-Bis(trimethylsilyl)acetamide, with the CAS number 10416-58-7, is a chemical compound commonly used as a silylating agent in organic synthesis. It features a central acetamide structure where two trimethylsilyl groups are attached to the nitrogen atom. This compound is characterized by its ability to enhance the volatility and stability of various organic compounds, making it particularly useful in gas chromatography and mass spectrometry. It is typically a colorless to pale yellow liquid with a relatively low boiling point, indicating its volatility. N,N-Bis(trimethylsilyl)acetamide is also known for its reactivity, particularly in the formation of silyl derivatives, which can facilitate the analysis of functional groups in organic molecules. Additionally, it is soluble in common organic solvents, which broadens its applicability in various chemical reactions. Safety precautions should be observed when handling this compound, as it can be irritant and may pose health risks if inhaled or ingested.

Formula: C₈H₂₁NOSi₂

InChI: InChI=1S/C8H21NOSi2/c1-8(10)9(11(2,3)4)12(5,6)7/h1-7H3

InChI key: InChIKey=VTACLVUOTMPORB-UHFFFAOYSA-N

SMILES: N([Si](C)(C)C)([Si](C)(C)C)C(C)=O

Synonyms:

• N,N-Bis(trimethylsilyl)acetamide
• NSC 269575
• Acetamide, N,N-bis(trimethylsilyl)-