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CAS 104180-23-6

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renin substrate tetradecapeptide human

Description:
Renin substrate tetradecapeptide, also known as angiotensinogen, is a peptide involved in the renin-angiotensin system, which plays a crucial role in regulating blood pressure and fluid balance in the human body. This peptide consists of 14 amino acids and serves as the precursor to angiotensin I, which is subsequently converted to angiotensin II, a potent vasoconstrictor. The structure of this peptide is characterized by specific sequences that allow it to interact with the enzyme renin, which cleaves it to produce angiotensin I. The biological activity of this peptide is essential for maintaining cardiovascular homeostasis, and its dysregulation can lead to various health issues, including hypertension and heart disease. The CAS number 104180-23-6 uniquely identifies this substance in chemical databases, facilitating research and development in pharmacology and biochemistry. Overall, renin substrate tetradecapeptide is a vital component of the endocrine system, influencing numerous physiological processes.
Formula:C83H122N24O19
Synonyms:
  • H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Asn-OH
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