CAS 1042019-87-3

Di-O-cysteinyl-glycinoyl Curcumin-d6

Controlled Product

CAS: 1042019-87-3

Formula: C₃₁D₆H₃₀N₄O₁₀S₂

Color and Shape: Neat

Molecular weight: 694.805

Ref: TR-D455602

Di-O-cysteinyl-glycinoyl Curcumin 90%

Controlled Product

CAS: 1042019-87-3

Applications Di-O-cysteinyl-glycinoyl curcumin is a metabolite of curcumin (C838500), which is a natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers disease (C
References Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953), Tu, B., et al.: J .Cell Biol., 164, 341 (2004), Xu, G., et al.: Biochemistry, 44, 9817 (2005), Johnson, J., et al.: Cancer Lett., 255, 170 (2007), Chem. and Eng. News 90(31), 44 (2012)

Formula: C₃₁H₃₆N₄O₁₀S₂

Purity: 90%

Color and Shape: Neat

Molecular weight: 688.77

Ref: TR-D455600