CAS 104227-86-3: 6-Deoxypenciclovir

Description: 6-Deoxypenciclovir is an antiviral compound primarily studied for its potential in treating herpesvirus infections. It is a derivative of penciclovir, which is known for its activity against herpes simplex virus (HSV) and varicella-zoster virus (VZV). The chemical structure of 6-deoxypenciclovir features a modified side chain that enhances its pharmacological properties. This compound exhibits characteristics typical of nucleoside analogs, including the ability to inhibit viral DNA polymerase, thereby interfering with viral replication. Its mechanism of action involves selective incorporation into viral DNA, leading to chain termination. The compound is generally characterized by its stability and solubility in various solvents, which can influence its bioavailability and therapeutic efficacy. Research into 6-deoxypenciclovir continues to explore its potential advantages over existing antiviral therapies, including reduced resistance and improved safety profiles. As with many antiviral agents, the effectiveness and safety of 6-deoxypenciclovir are subject to ongoing clinical evaluation.

Formula: C₁₀H₁₅N₅O₂

InChI: InChI=1S/C10H15N5O2/c11-10-12-3-8-9(14-10)15(6-13-8)2-1-7(4-16)5-17/h3,6-7,16-17H,1-2,4-5H2,(H2,11,12,14)

InChI key: InChIKey=WJOWACPJSFGNRM-UHFFFAOYSA-N

SMILES: OCC(CO)CCN1C=NC=2C=NC(=NC21)N

Synonyms:

• 1,3-Propanediol, 2-(2-(2-amino-9H-purin-9-yl)ethyl)-
• 2-Amino-9-(4-hydroxy-3-hydroxymethylbut-1-yl)purine
• 2-[2-(2-Aminopurin-9-yl)ethyl]propane-1,3-diol
• 2-[2-(2-amino-9H-purin-9-yl)ethyl]propane-1,3-diol
• 6-Deoxy Penciclovir
• 6-Deoxypenciclovir
• Brl 42359
• Di-Desacetyl Famciclovir
• DidesacetylFamciclovir,BRL42359
• 2-[2-(2-Amino-9H-purin-9-yl)ethyl]-1,3-propanediol

1,3-Propanediol, 2-[2-(2-amino-9H-purin-9-yl)ethyl]-

CAS: 104227-86-3

• Formula: C₁₀H₁₅N₅O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 237.2584

6-DEOXYPENCICLOVIR

CAS: 104227-86-3

• Purity: 95%
• Molecular weight: 237.26300048828125

6-Deoxypenciclovir

CAS: 104227-86-3

Applications A metabolite of Famciclovir, an antiviral. References Harnden, M.R., et al.: J. Med. Chem., …

• Formula: C₁₀H₁₅N₅O₂
• Color and Shape: Off White Solid
• Molecular weight: 237.26

6-Deoxypenciclovir

CAS: 104227-86-3

6-Deoxypenciclovir is an oral prodrug of penciclovir that is hydrolyzed to penciclovir in vivo. This …

• Formula: C₁₀H₁₅N₅O₂
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 237.26 g/mol