CAS 104286-02-4

(11β)-17-[(Ethoxycarbonyl)oxy]-11,21-dihydroxypregna-1,4-diene-3,20-dione

Description:

The chemical substance known as (11β)-17-[(Ethoxycarbonyl)oxy]-11,21-dihydroxypregna-1,4-diene-3,20-dione, with the CAS number 104286-02-4, is a synthetic steroid derivative. It features a pregnane backbone, which is characteristic of many steroid hormones, and contains multiple functional groups that contribute to its biological activity. The presence of hydroxyl (-OH) groups at the 11 and 21 positions indicates potential for hydrogen bonding and solubility in polar solvents. The ethoxycarbonyl group suggests that this compound may have ester-like properties, which can influence its pharmacokinetics and bioavailability. This compound is likely to exhibit anti-inflammatory and immunosuppressive properties, similar to other corticosteroids, due to its structural similarities. Its specific interactions with biological targets, such as glucocorticoid receptors, would determine its therapeutic applications. Overall, this compound represents a class of steroids that are important in medicinal chemistry and pharmacology, particularly in the development of anti-inflammatory drugs.

Formula: C₂₄H₃₂O₇

InChI: InChI=1/C24H32O7/c1-4-30-21(29)31-24(19(28)13-25)10-8-17-16-6-5-14-11-15(26)7-9-22(14,2)20(16)18(27)12-23(17,24)3/h7,9,11,16-18,20,25,27H,4-6,8,10,12-13H2,1-3H3/t16-,17-,18-,20+,22-,23-,24-/m0/s1

InChI key: InChIKey=CWVNDXWCEADDCU-ZJUZSDNKSA-N

SMILES: O(C(OCC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])[H]

Synonyms:

• (11Beta)-11,21-Dihydroxy-3,20-Dioxopregna-1,4-Dien-17-Yl Ethyl Carbonate
• (11β)-17-[(Ethoxycarbonyl)oxy]-11,21-dihydroxypregna-1,4-diene-3,20-dione
• 17-((Ethoxycarbonyl)oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione (11beta)-
• Pred-17-etc
• Prednisolone 17-(ethyl carbonate)
• Pregna-1,4-diene-3,20-dione, 17-((ethoxycarbonyl)oxy)-11,21-dihydroxy-, (11beta)-
• Pregna-1,4-diene-3,20-dione, 17-[(ethoxycarbonyl)oxy]-11,21-dihydroxy-, (11β)-
• Prednisolone 17-ethylcarbonate

Prednicarbate Related Compound B (Prednisolone-17-ethylcarbonate)

CAS: 104286-02-4

Adrenal cortical hormones and their derivatives nesoi

Formula: C₂₄H₃₂₀₇

Color and Shape: White Crystalline Powder

Molecular weight: 432.51

Ref: 45-1554920

Prednisolone 17-Ethyl Carbonate

CAS: 104286-02-4

Applications A metabolite of Prednicarbate (P703700).
References Kumar, R., et al.: Steroids, 64, 310 (1999), Kauppi, B., et al.: Biol. Chem., 278, 22748 (2003), Buchwald, P., et al.: J. Med. Chem., 49, 883 (2006),

Formula: C₂₄H₃₂O₇

Color and Shape: White To Off-White

Molecular weight: 432.51

Ref: TR-P703730

Prednisolone 17-ethyl carbonate

Controlled Product

CAS: 104286-02-4

Prednisolone 17-ethyl carbonate is a glucocorticoid that is used for the treatment of inflammatory skin diseases. Prednisolone 17-ethyl carbonate has been shown to inhibit the production of cytokines and chemokines in vitro, which are important mediators of inflammation. It also inhibits the production of proinflammatory mediators such as prostaglandin E2, leukotriene B4, and nitric oxide. Prednisolone 17-ethyl carbonate can be used to treat inflammatory skin diseases such as atopic dermatitis, psoriasis, eczema, and erythroderma. It has been shown to have a higher anti-inflammatory potency than betamethasone or fluocinolone acetonide in clinical studies with other corticosteroids. This drug is also able to bind to glucocorticoid receptors in skin cells and inhibit the production of proteins that cause inflammation by binding to its receptor

Formula: C₂₄H₃₂O₇

Purity: Min. 95%

Molecular weight: 432.51 g/mol

Ref: 3D-FP27132

Prednisolone 17-Ethyl Carbonate

CAS: 104286-02-4

Formula: C₂₄H₃₂O₇

Molecular weight: 432.51

Ref: ST-EA-CP-P20026