CAS 1043-21-6
:pirenoxine
Description:
Pirenoxine, with the CAS number 1043-21-6, is a chemical compound primarily known for its application in ophthalmology. It is classified as a pyrimidine derivative and is recognized for its role as a protective agent for the retina. The substance exhibits antioxidant properties, which help in mitigating oxidative stress in retinal cells, making it beneficial in the treatment of certain eye conditions, such as retinitis pigmentosa and other degenerative retinal diseases. Pirenoxine is typically administered in the form of eye drops, allowing for localized treatment with minimal systemic absorption. Its mechanism of action involves stabilizing cell membranes and preventing damage from free radicals. Additionally, pirenoxine has been studied for its potential neuroprotective effects, contributing to its therapeutic profile. While it is generally well-tolerated, like any medication, it may have side effects, and its use should be guided by a healthcare professional. Overall, pirenoxine represents a significant advancement in the field of ocular therapeutics.
Formula:C16H8N2O5
InChI:InChI=1/C16H8N2O5/c19-9-5-8(16(21)22)18-14-10(20)6-12-15(13(9)14)17-7-3-1-2-4-11(7)23-12/h1-6H,(H,18,19)(H,21,22)
InChI key:InChIKey=OKPNYGAWTYOBFZ-UHFFFAOYSA-N
SMILES:OC1=C2C=3C(OC=4C(N3)=CC=CC4)=CC(=O)C2=NC(C(O)=O)=C1
Synonyms:- 1,5-Dioxo-4H-pyrido[3,2-a]phenoxazine-3-carboxylic acid
- 1,5-dioxo-1,5-dihydro-4H-pyrido[3,2-a]phenoxazine-3-carboxylic acid
- 1-Hydroxy-3-carboxy-5H-pyrido[3,2-a]phenoxazin-5-one
- 1-Hydroxy-5-oxo-5H-pyrido[3,2-a]phenoxazine-3-carboxylic acid
- 1-Hydroxy-5H-pyrido-[3,2-a]phenoxazin-5-one-3-carboxylic Acid
- 1043-21-6
- 257-181-6
- 5H-Pyrido[3,2-a]phenoxazine-3-carboxylic acid, 1-hydroxy-5-oxo-
- Catalin
- Catalin (pharmaceutical)
- Catalin K
- Clarvisan
- Kary-Uni
- Pirfenoxone
- Pyrphenoxone
- Bernetine
- Catalin【opthalmic remedy】
- 1-Hydroxy-5-oxo-5H-pyrido[3,2-]phenoxazine-3-carboxylicacid
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Found 4 products.
Pirenoxine
CAS:<p>Pirenoxine is an agent with anti-cataractogenesis activity by interacting with calcium ions or selenite which could lead to the formation of lens cataract.</p>Formula:C16H8N2O5Color and Shape:SolidMolecular weight:308.25Pirenoxine
CAS:Controlled Product<p>Applications Pirenoxine, is a medication used in the possible treatment and prevention of cataracts.<br>References Liao, J. H. et al.: Inorganic Chemistry. 50 (1): 365–377.<br></p>Formula:C16H8N2O5Color and Shape:NeatMolecular weight:308.25Pirenoxine
CAS:<p>Pirenoxine is a synthetic drug that is used as an antimicrobial agent. It has been shown to protect corneal endothelial cells from oxidative injury. Pirenoxine reacts with the sulfhydryl groups of proteins and forms disulfide bonds. This reaction prevents protein denaturation and protects against oxidative stress by scavenging free radicals. The structure of pirenoxine was determined using particle-beam and synchronous fluorescence techniques, which showed it to have a calcium binding site in addition to its previously known calcium pantothenate site. Pirenoxine has been shown to have a physiological function of regulating the release of catecholamines from adrenal medulla or from nerve terminals in response to stimulation by acetylcholine or other agonists.</p>Formula:C16H8N2O5Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:308.25 g/mol



