CAS 104344-23-2: Bisoprolol fumarate
Description:Bisoprolol fumarate is a selective beta-1 adrenergic receptor blocker primarily used in the management of hypertension and heart failure. It is a white to off-white crystalline powder that is soluble in water and methanol, but less soluble in organic solvents like chloroform and ether. The substance is characterized by its ability to reduce heart rate and myocardial contractility, making it effective in lowering blood pressure and improving cardiac function. Bisoprolol fumarate is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. The fumarate salt form enhances its stability and solubility, facilitating better absorption in the gastrointestinal tract. As with other beta-blockers, it may have side effects such as fatigue, dizziness, and bradycardia, and it should be used with caution in patients with asthma or certain cardiovascular conditions. Overall, Bisoprolol fumarate is an important therapeutic agent in cardiovascular medicine, contributing to improved patient outcomes in various heart-related conditions.
Formula:C18H31NO4C4H4O4
InChI:InChI=1S/C18H31NO4.C4H4O4/c1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
InChI key:InChIKey=RZPZLFIUFMNCLY-WLHGVMLRSA-N
SMILES:O=C(O)C=CC(=O)O.OC(COC1=CC=C(C=C1)COCCOC(C)C)CNC(C)C
- Synonyms:
- (2R)-1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol
- 1-(4-((2-Isopropoxyethoxy)methyl)phenoxy)-3-(isopropylamino)propan-2-ol hemifumarate
- 1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol (2E)-but-2-enedioate (2:1) (salt)
- 1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol (2E)-but-2-enedioate (salt)
- 1-(Propan-2-Ylamino)-3-(4-{[2-(Propan-2-Yloxy)Ethoxy]Methyl}Phenoxy)Propan-2-Ol
- 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (2E)-2-butenedioate (2:1)
- 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (2E)-2-butenedioate (2:1) (salt)
- 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (E)-2-butenedioate (2:1) (salt)
- Bisoprolol Fumarate
- Bisoprolol fumerate
- See more synonyms
- Concor
- Detensiel
- Emcor
- Emd 33512
- Emvoncor
- Eurtadal
- Isoten
- Maintate
- Monocor
- Soprol
- Zebeta