CAS 10447-39-9

Quifenadine

Description:

Quifenadine is an antihistamine compound primarily used for its anti-allergic properties. It is classified as a second-generation antihistamine, which means it is less likely to cause sedation compared to first-generation antihistamines. The chemical structure of Quifenadine includes a piperidine ring, contributing to its pharmacological activity. It functions by selectively blocking H1 histamine receptors, thereby alleviating symptoms associated with allergic reactions, such as sneezing, itching, and runny nose. Quifenadine is typically administered orally and is known for its relatively favorable side effect profile. Its solubility characteristics suggest it is more soluble in organic solvents than in water, which can influence its formulation in pharmaceutical preparations. As with many antihistamines, caution is advised in patients with certain medical conditions, and it may interact with other medications. Overall, Quifenadine represents a useful option in the management of allergic symptoms, reflecting the ongoing development of targeted therapies in allergy treatment.

Formula: C₂₀H₂₃NO

InChI: InChI=1S/C20H23NO/c22-20(17-7-3-1-4-8-17,18-9-5-2-6-10-18)19-15-21-13-11-16(19)12-14-21/h1-10,16,19,22H,11-15H2

InChI key: InChIKey=PZMAHNDJABQWGS-UHFFFAOYSA-N

SMILES: C(O)(C1C2CCN(C1)CC2)(C3=CC=CC=C3)C4=CC=CC=C4

Synonyms:

• (1-Aza-bicyclo[2.2.2]oct-3-yl)-diphenyl-methanol
• (3-Quinuclidinyl)Diphenyl Carbinol Hydrochloride
• 1-Azabicyclo(2.2.2)octane-3-methanol, alpha,alpha-diphenyl-
• 1-Azabicyclo[2.2.2]Oct-3-Yl(Diphenyl)Methanol
• 1-Azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol
• 1-Azabicyclo[2.2.2]octane-3-methanol, α,α-diphenyl-
• 3-Quinuclidinemethanol, alpha,alpha-diphenyl-
• 3-Quinuclidinemethanol, α,α-diphenyl-
• Benzhydrol, alpha-(3-quinuclidinyl)-
• Brn 1542055
• Diphenyl-3-quinuclidylcarbinol
• Quifenadine [INN]
• Quifenadino
• Quifenadino [INN-Spanish]
• Quifenadinum
• Quifenadinum [INN-Latin]
• Unii-W9A18Rj49B
• alpha,alpha-Diphenyl-3-chinuclidinylmethanol
• alpha,alpha-Diphenyl-3-quinuclidinemethanol
• α,α-Diphenyl-1-azabicyclo[2.2.2]octane-3-methanol

Soclenicant

CAS: 10447-39-9

Soclenicant

Purity: ≥98%

Molecular weight: 418.49g/mol

Ref: 54-BUP20706

Quifenadine

Controlled Product

CAS: 10447-39-9

Applications Quifenadine is used in the biological studies of azoniabicyclooctanes as muscarinic acetylcholine receptor antagonists.
References Laine, D. I., et al.: J. Med. Chem., 52, 2493 (2009);

Formula: C₂₀H₂₃NO

Color and Shape: Neat

Molecular weight: 293.4

Ref: TR-Q536000

Quifenadine-d10

Controlled Product

CAS: 10447-39-9

Stability Hygroscopic
Applications Quifenadine-d10 is the isotope labelled analog of Quifenadine. Quifenadine is used in the biological studies of azoniabicyclooctanes as muscarinic acetylcholine receptor antagonists.
References Laine, D. I., et al.: J. Med. Chem., 52, 2493 (2009);

Formula: C₂₀H₁₃D₁₀NO

Color and Shape: Neat

Molecular weight: 303.46

Ref: TR-Q536002

Quifenadine

CAS: 10447-39-9

Quifenadine, an H1-histamine receptor blocker, has antiarrhythmic properties.

Formula: C₂₀H₂₃NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 293.4

Ref: TM-T20951