CAS 104486-81-9

Mupirocin Calcium

Description:

Mupirocin calcium, with the CAS number 104486-81-9, is an antibiotic agent primarily used for the treatment of bacterial infections, particularly those caused by Staphylococcus aureus, including methicillin-resistant strains (MRSA). It is a topical antibiotic that works by inhibiting bacterial protein synthesis, specifically targeting the isoleucyl-tRNA synthetase enzyme. Mupirocin is derived from the fermentation of the bacterium Pseudomonas fluorescens and is known for its effectiveness against gram-positive bacteria. The calcium salt form enhances its stability and solubility, making it suitable for pharmaceutical formulations. Mupirocin is commonly available as a cream or ointment for external use, and it is often prescribed for skin infections, such as impetigo and folliculitis. Its localized application minimizes systemic absorption, reducing the risk of side effects. However, prolonged use can lead to bacterial resistance, necessitating careful consideration of its application in clinical settings.

Formula: C₂₆H₄₆CaO₉

InChI: InChI=1/2C26H44O9.Ca.2H2O/c2*1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27;;;/h2*13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29);;2*1H2/q;;+2;;/p-2/b2*16-13+;;;/t2*17-,18-,19-,20-,21-,24+,25-,26-;;;/m00.../s1

Synonyms:

• Mupirocin calcium anhydrous
• Brl 4910F
• Bactroban Nasal
• Calcium mupirocin
• L-talo-Non-2-enoic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-((3-(2-hydroxy-1-methylpropyl)oxiranyl)methyl)-3-methyl-, 8-carboxyoctyl ester, calcium salt (2:1), (2E,8(2S,3S(1S,2S)))-
• L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-(((2S,3S)-3-((1S,2S)-2-hydroxy-1-methylpropyl)oxiranyl)methyl)-3-methyl-, 8-carboxyoctyl ester, calium salt (2:1), (2E)-
• Nonanoic acid, 9-((3-methyl-1-oxo-4-(tetrahydro-3,4-dihydroxy-5-((3-(2-hydroxy-1-methylpropyl)oxiranyl)methyl)-2H-pyran-2-yl)-2-butenyl)oxy)-, calcium salt (2:1) (2S-(2alpha(E),3beta,4beta,5alpha(2R*,3R*(1R*,2R*))))-
• calcium bis[9-({(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl}oxy)nonanoate] dihydrate (non-preferred name)
• Mupirocin calcium
• L-talo-Non-2-enonicacid,5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]-2-oxiranyl]methyl]-3-methyl-,8-carboxyoctyl ester, calcium salt (2:1), (2E)-

Mupirocin calcium

CAS: 104486-81-9

Mupirocin calcium, an antibiotic from Pseudomonas fluorescens, halts bacterial protein and RNA synthesis.

Formula: C₂₆H₄₄O₉Ca

Color and Shape: Solid

Molecular weight: 519.65

Ref: TM-T75304

Mupirocin calcium

CAS: 104486-81-9

Inhibitor of isoleucyl-tRNA synthetase; inhibitor of protein synthesis

Formula: C₂₆H₄₄O₉Ca

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 520.66 g/mol

Ref: 3D-AM138525

Mupirocin Calcium

CAS: 104486-81-9

Formula: C₂₆H₄₄O₉Ca

Molecular weight: 499.62 : 40.08

Ref: ST-EA-CP-M50007