CAS 10455-93-3

(5beta)-17-hydroxypregnane-3,11,20-trione

Description:

(5beta)-17-hydroxypregnane-3,11,20-trione, also known as 17-hydroxyprogesterone, is a steroid hormone that plays a crucial role in the regulation of various physiological processes, including the menstrual cycle and pregnancy. This compound is characterized by its three ketone groups located at positions 3, 11, and 20, along with a hydroxyl group at position 17. It is a derivative of progesterone and is involved in the biosynthesis of other steroid hormones. The presence of the hydroxyl group contributes to its solubility in polar solvents, while the ketone groups influence its reactivity and biological activity. This substance is primarily produced in the adrenal glands and gonads and is essential for maintaining pregnancy and supporting fetal development. Clinically, it is often measured to assess adrenal function and diagnose conditions related to steroid hormone imbalances. Its CAS number, 10455-93-3, is a unique identifier that facilitates the identification and study of this compound in scientific literature and databases.

Formula: C₂₁H₃₀O₄

InChI: InChI=1/C21H30O4/c1-12(22)21(25)9-7-16-15-5-4-13-10-14(23)6-8-19(13,2)18(15)17(24)11-20(16,21)3/h13,15-16,18,25H,4-11H2,1-3H3/t13-,15+,16+,18-,19+,20+,21+/m1/s1

Synonyms:

• 5.beta.-Pregnane-3,11,20-trione, 17-hydroxy-

17-Hydroxy-5β-pregnane-3,11,20-trione

Controlled Product

CAS: 10455-93-3

Applications 17-Hydroxy-5β-pregnane-3,11,20-trione is an related compound to cortisone (C696500), an glucocorticoid used as an anti-inflammatory agent.
References Levin, R.H., et al.: J. Am. Chem. Soc., 76, 546 (1954); Menini, E., et al.: Biochem. J., et al.: 84, 195 (1962);

Formula: C₂₁H₃₀O₄

Color and Shape: Neat

Molecular weight: 346.46

Ref: TR-H952260

17-Hydroxy-5β-pregnane-3,11,20-trione

CAS: 10455-93-3

Formula: C₂₁H₃₀O₄

Molecular weight: 346.47

Ref: ST-EA-CP-C244003