CAS 104612-35-3

(S)-N-Methylhydroxysuccinimide

Description:

(S)-N-Methylhydroxysuccinimide is a chiral compound characterized by its unique structural features, which include a hydroxysuccinimide moiety and a methyl group attached to the nitrogen atom. This compound is often utilized in organic synthesis and bioconjugation reactions due to its ability to selectively react with amines, forming stable amide bonds. The presence of the hydroxyl group enhances its reactivity and solubility in polar solvents, making it suitable for various applications in medicinal chemistry and biochemistry. As a chiral molecule, it can exist in two enantiomeric forms, with the (S)-configuration being particularly relevant for applications requiring stereoselectivity. Its CAS number, 104612-35-3, allows for easy identification and retrieval of information in chemical databases. Overall, (S)-N-Methylhydroxysuccinimide is valued for its reactivity, solubility, and role in facilitating the formation of complex biomolecules in research and pharmaceutical development.

Formula: C₅H₇NO₃

InChI: InChI=1S/C5H7NO3/c1-6-4(8)2-3(7)5(6)9/h3,7H,2H2,1H3/t3-/m0/s1

InChI key: InChIKey=NLKACWKSCREJEL-VKHMYHEASA-N

SMILES: O=C1N(C)C(=O)C[C@@H]1O

Synonyms:

• (3S)-3-Hydroxy-1-methyl-2,5-pyrrolidinedione
• (3S)-3-hydroxy-1-methylpyrrolidine-2,5-dione
• (S)-3-hydroxy-1-methylpyrrolidine-2,5-dione
• (S)-N-Methylhydroxysuccinimide
• 2,5-Pyrrolidinedione 3-hydroxy-1-methyl-, (3S)-
• 2,5-Pyrrolidinedione, 3-hydroxy-1-methyl-, (S)-

(3S)-3-Hydroxy-1-methyl-2,5-pyrrolidinedione

CAS: 104612-35-3

Formula: C₅H₇NO₃

Color and Shape: Solid

Molecular weight: 129.1140

Ref: IN-DA003CO4

(S)-N-Methylhydroxysuccinimide-d3

Controlled Product

CAS: 104612-35-3

Applications (S)-N-Methylhydroxysuccinimide-d3 is a labelled analog of (S)-N-Methylhydroxysuccinimide (M312895) which is a Hydroxysuccinimide derivative.
References Sleevi, M., et al.: J. Med. Chem., 34, 1314 (1991),

Formula: C₅H₄D₃NO₃

Color and Shape: Neat

Molecular weight: 132.13

Ref: TR-M312897

(S)-N-Methylhydroxysuccinimide

CAS: 104612-35-3

Applications A Hydroxysuccinimide derivative.
References Sleevi, M., et al.: J. Med. Chem., 34, 1314 (1991),

Formula: C₅H₇NO₃

Color and Shape: Neat

Molecular weight: 129.11

Ref: TR-M312895

(S)-N-Methylhydroxysuccinimide

CAS: 104612-35-3

N-Methylhydroxysuccinimide is a reagent used in chemical synthesis, including the production of 3-indoxyl-beta-D-galactopyranoside. It has been shown to be safe for human use by short-term exposure and uptake studies in Sprague-Dawley rats. N-Methylhydroxysuccinimide is not carcinogenic and does not cause adverse effects to the liver or kidney, based on animal experiments. This compound also has an analytical method that can be used to determine its concentration in urine samples from humans.

Formula: C₅H₇NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 129.11 g/mol

Ref: 3D-FM25856