CAS 104632-27-1

2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N⁶-propyl-, hydrochloride (1:2), (6R)-

Description:

2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N^6-propyl-, hydrochloride (1:2), (6R)-, identified by CAS number 104632-27-1, is a chemical compound characterized by its unique bicyclic structure that incorporates both benzothiazole and diamine functionalities. This compound typically appears as a hydrochloride salt, which enhances its solubility in water and makes it suitable for various applications, particularly in pharmaceutical and biochemical contexts. The presence of the tetrahydro group contributes to its potential biological activity, while the propyl substituent may influence its lipophilicity and interaction with biological targets. The stereochemistry indicated by (6R) suggests specific spatial arrangements that can affect the compound's reactivity and interactions. Overall, this substance may exhibit properties relevant to medicinal chemistry, including potential use as a therapeutic agent or in research applications, although specific biological activities and mechanisms would require further investigation. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity or reactivity.

Formula: C₁₀H₁₉Cl₂N₃S

InChI: InChI=1S/C10H17N3S.2ClH/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8;;/h7,12H,2-6H2,1H3,(H2,11,13);2*1H/t7-;;/m1../s1

InChI key: InChIKey=QMNWXHSYPXQFSK-XCUBXKJBSA-N

SMILES: NC1=NC2=C(C[C@H](NCCC)CC2)S1.Cl

Synonyms:

• (R)-4,5,6,7-Tetrahydro-6-(propylamino)-benzothiazole-2-amine dihydrochloride
• SND 919CL2X
• 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, dihydrochloride, (6R)-
• 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, dihydrochloride, (R)-
• 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, hydrochloride (1:2), (6R)-
• KNS-760704 dihydrochloride
• Kns 760704
• (R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride // (R)-Pramipexole dihydrochloride
• (R)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine dihydrochloride
• DexpraMipexole (dihydrochloride)
• (R)-Pramipexole (hydrochloride)
• Pramipexole EP Impurity D ((R)-Pramipexole diHCl)
• Dexpramipexole dihydrochloride
• Pramipexole Related Compound D ((R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydro (1553815)
• Pramipexole Dihydrochloride Hydrate IMP
• RPPX
• (6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine,dihydrochloride
• Pramipexole impurity D CRS
• Dexpramipexole HCl
• (R)-PRAMIPEXOLE DIHYDROCHLORIDE; KNS 760704; SND 919CL2X
• PraMipexole IMpurity D
• Pramipexole dihydrochloride impurity IV
• Pramipexole R-Isomer
• Pramipexole Dihydrochloride Hydrate Impurity
• Pramipexole EP Impurity D DiHCl

PRAMIPEXOLE IMPURITY D CRS

CAS: 104632-27-1

PRAMIPEXOLE IMPURITY D CRS

Formula: C₁₀H₁₉Cl₂N₃S

Color and Shape: Powder.

Molecular weight: 284.249

Ref: 41-Y0001267

Pramipexole Related Compound D ((R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride)

CAS: 104632-27-1

Compounds containing a benzothiazole ring-system (wheth

Formula: C₁₀H₁₇N₃S·2HCl

Color and Shape: Off-White Powder

Molecular weight: 283.06767

Ref: 45-1553815

Dexpramipexole dihydrochloride

CAS: 104632-27-1

Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine

Formula: C₁₀H₁₉Cl₂N₃S

Purity: 99.75% - 99.88%

Color and Shape: Solid

Molecular weight: 284.25

Ref: TM-T11011

(R)-Pramipexole (hydrochloride)

CAS: 104632-27-1

Formula: C₁₀H₁₈ClN₃S

Purity: %

Color and Shape: Solid

Molecular weight: 247.7880

Ref: IN-DA008SSY

Dexpramipexole dihydrochloride

CAS: 104632-27-1

Dexpramipexole dihydrochloride

Purity: ≥98%

Molecular weight: 284.25g/mol

Ref: 54-BUP10920

Pramipexole EP Impurity D DiHCl (Pramipexole USP Related Compound D)

CAS: 104632-27-1

Formula: C₁₀H₁₇N₃S·2HCl

Color and Shape: White To Off-White Solid

Molecular weight: 211.33 2 36.46

Ref: 4Z-P-125

(R)-Pramipexole Dihydrochloride

Controlled Product

CAS: 104632-27-1

Impurity Pramipexole EP Impurity D; Pramipexole BP Impurity D; Pramipexole USP Related Compound D
Applications (R)-Pramipexole Dihydrochloride (Pramipexole EP Impurity D; Pramipexole BP Impurity D; Pramipexole USP Related Compound D) is the opposite enantiomer of Pramipexole (P700755), a dopamine-D2-receptor agonist. Dexpramipexole is a low-molecular-weight, water-soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics.
References Mierau, J., et al.: J. Med. Chem., 30, 494 (1987), Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)

Formula: C₁₀H₁₇N₃S·2ClH

Color and Shape: Neat

Molecular weight: 284.25

Ref: TR-P700745

Dexpramipexole dihydrochloride

CAS: 104632-27-1

Purity: 99.71%

Molecular weight: 284.24

Ref: 10-F979620