CAS 104632-28-2

(R)-Pramipexole

Description:

(R)-Pramipexole is a chiral compound primarily recognized as a dopamine agonist, commonly used in the treatment of Parkinson's disease and restless legs syndrome. Its chemical structure features a bicyclic core that allows it to selectively bind to dopamine receptors, particularly the D2 and D3 subtypes, thereby mimicking the action of dopamine in the brain. This characteristic makes it effective in alleviating motor symptoms associated with dopamine deficiency. The compound is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. (R)-Pramipexole exhibits a favorable pharmacokinetic profile, with a relatively long half-life, allowing for once-daily dosing in clinical settings. Additionally, it has been noted for its potential neuroprotective properties, which may contribute to its therapeutic effects. Side effects can include nausea, dizziness, and fatigue, which are common with dopaminergic therapies. Overall, (R)-Pramipexole represents a significant advancement in the management of dopamine-related disorders.

Formula: C₁₀H₁₇N₃S

InChI: InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m1/s1

InChI key: InChIKey=FASDKYOPVNHBLU-SSDOTTSWSA-N

SMILES: NC1=NC2=C(C[C@H](NCCC)CC2)S1

Synonyms:

• (6R)-4,5,6,7-Tetrahydro-N⁶-propyl-2,6-benzothiazolediamine
• (6R)-6-N-Propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
• (6R)-N6-Propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
• (R)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole
• (R)-4,5,6,7-Tetrahydro-6-(propylamino)-benzothiazole-2-amine
• (R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine
• (R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine Dihydrochloride
• (R)-Pramipexole Dihydrochloride
• 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N⁶-propyl-, (6R)-
• 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N⁶-propyl-, (R)-
• Dexpramipexole
• R-(+)-Pramipexole
• (6R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine
• (R)-Pramipexole
• R-(+)-Pramipexole
• 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, (6R)-
• 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, (R)-
• Pramipexole Related Compound D (25 mg) ((R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride)
• PraMipexole Related CoMpound D
• (R)-N6-Propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
• 2,6-BenzothiazolediaMine, 4,5, 6,7-tetrahydro-N6-propyl-, (6R)-
• Pramipexole Related Compound D (25 mg) ((R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole)

(6R)-N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine

CAS: 104632-28-2

Formula: C₁₀H₁₇N₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 211.3271

Ref: IN-DA007GX7

Dexpramipexole

CAS: 104632-28-2

Dexpramipexole

Purity: ≥98%

Molecular weight: 211.33g/mol

Ref: 54-BUP16400

Dexpramipexole

CAS: 104632-28-2

Dexpramipexole ((R)-Pramipexole) is a mitochondrial protective agent that maintains mitochondrial function and energy production.

Formula: C₁₀H₁₇N₃S

Purity: 99.78%

Color and Shape: Solid

Molecular weight: 211.33

Ref: TM-TQ0175

Pramipexole EP Impurity D

CAS: 104632-28-2

Formula: C₁₀H₁₇N₃S

Molecular weight: 211.33

Ref: ST-EA-CP-P21004

(R)-N6-Propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine

CAS: 104632-28-2

Purity: ≥98%

Molecular weight: 211.3300018310547

Ref: 10-F234127

(R)-Pramipexole 2HCl

Controlled Product

CAS: 104632-28-2

Dopamine (D2 and D3) receptor agonist; has anti-parkinsonian effects

Formula: C₁₀H₁₉Cl₂N₃S

Purity: Min. 95%

Molecular weight: 283.06767

Ref: 3D-FP27117