CymitQuimica logo

CAS 104632-28-2

:

(R)-Pramipexole

Description:
(R)-Pramipexole is a chiral compound primarily recognized as a dopamine agonist, commonly used in the treatment of Parkinson's disease and restless legs syndrome. Its chemical structure features a bicyclic core that allows it to selectively bind to dopamine receptors, particularly the D2 and D3 subtypes, thereby mimicking the action of dopamine in the brain. This characteristic makes it effective in alleviating motor symptoms associated with dopamine deficiency. The compound is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. (R)-Pramipexole exhibits a favorable pharmacokinetic profile, with a relatively long half-life, allowing for once-daily dosing in clinical settings. Additionally, it has been noted for its potential neuroprotective properties, which may contribute to its therapeutic effects. Side effects can include nausea, dizziness, and fatigue, which are common with dopaminergic therapies. Overall, (R)-Pramipexole represents a significant advancement in the management of dopamine-related disorders.
Formula:C10H17N3S
InChI:InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m1/s1
InChI key:InChIKey=FASDKYOPVNHBLU-SSDOTTSWSA-N
SMILES:NC1=NC2=C(C[C@H](NCCC)CC2)S1
Synonyms:
  • (6R)-4,5,6,7-Tetrahydro-N<sup>6</sup>-propyl-2,6-benzothiazolediamine
  • (6R)-6-N-Propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
  • (6R)-N6-Propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
  • (R)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole
  • (R)-4,5,6,7-Tetrahydro-6-(propylamino)-benzothiazole-2-amine
  • (R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine
  • (R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine Dihydrochloride
  • (R)-Pramipexole Dihydrochloride
  • 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N<sup>6</sup>-propyl-, (6R)-
  • 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N<sup>6</sup>-propyl-, (R)-
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 6 products.