CAS 10468-90-3

O-(4-hydroxyphenyl)-3-iodo-L-tyrosine

Description:

O-(4-hydroxyphenyl)-3-iodo-L-tyrosine, with the CAS number 10468-90-3, is a derivative of the amino acid tyrosine, characterized by the presence of an iodine atom and a hydroxyphenyl group. This compound features a phenolic hydroxyl group, which contributes to its potential antioxidant properties, and the iodine substitution can influence its reactivity and biological activity. The presence of the iodine atom may enhance the compound's lipophilicity, affecting its interaction with biological membranes and receptors. O-(4-hydroxyphenyl)-3-iodo-L-tyrosine is of interest in biochemical research, particularly in studies related to thyroid hormone activity and signaling pathways, as well as in the development of pharmaceuticals. Its structural modifications can lead to variations in solubility, stability, and bioavailability, making it a subject of interest in medicinal chemistry. Overall, this compound exemplifies the intricate relationship between molecular structure and biological function, highlighting the importance of functional groups in determining the properties of amino acid derivatives.

Formula: C₁₅H₁₄INO₄

InChI: InChI=1/C15H14INO4/c16-12-7-9(8-13(17)15(19)20)1-6-14(12)21-11-4-2-10(18)3-5-11/h1-7,13,18H,8,17H2,(H,19,20)/t13-/m0/s1

InChI key: InChIKey=SXQVOFSDWXYIRP-ZDUSSCGKSA-N

SMILES: O(C1=C(I)C=C(C[C@@H](C(O)=O)N)C=C1)C2=CC=C(O)C=C2

Synonyms:

• L-Tyrosine, O-(4-hydroxyphenyl)-3-iodo-
• 3-Monoiodothyronine
• O-(4-Hydroxyphenyl)-3-iodo-L-tyrosine
• 3-Iodo-L-thyronine
• Alanine, 3-[4-(p-hydroxyphenoxy)-3-iodophenyl]-, L-
• 3-[4-(p-Hydroxyphenoxy)-3-iodophenyl]-L-alanine
• 3-Iodo-O-(4-hydroxyphenyl)-L-tyrosine

3-Iodo-L-thyronine

CAS: 10468-90-3

Formula: C₁₅H₁₄INO₄

Color and Shape: Solid

Molecular weight: 399.1804

Ref: IN-DA008WPM

3-Iodo-L-thyronine

CAS: 10468-90-3

Molecular weight: 399.18

Ref: 7W-GM5041

3-Iodo-L-thyronine

CAS: 10468-90-3

Formula: C₁₅H₁₄INO₄

Color and Shape: Off-White To Brown

Molecular weight: 399.18

Ref: TR-I721500

3-Iodo-L-thyronine

CAS: 10468-90-3

3-Iodo-L-thyronine is a thyroid hormone that is synthesized from thyroxine. It has a high maximal response in humans and it may be useful for the treatment of hypothyroidism. 3-Iodo-L-thyronine is not active against rat liver microsomes because it is a noncompetitive inhibitor. The clinical relevance of this drug needs to be evaluated before it can be used as a therapeutic agent, but its analytical methods are similar to those used for other thyroid hormones, such as T3, T4, and 3,5,3'-triiodothyronine. This molecule has been successfully detected in human serum and tissues by using an analytical method based on iodoacetic acid.

Formula: C₁₅H₁₄INO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 399.18 g/mol

Ref: 3D-FI24618

3-Iodo-L-thyronine-13C6

CAS: 10468-90-3

Formula: C₆C₉H₁₄INO₄

Color and Shape: White To Red

Molecular weight: 405.136

Ref: TR-I721502