CAS 104721-52-0

Ofloxacin N-oxide

Description:

Ofloxacin N-oxide, with the CAS number 104721-52-0, is a derivative of the fluoroquinolone antibiotic ofloxacin. This compound is characterized by the presence of an N-oxide functional group, which is formed by the oxidation of the nitrogen atom in the piperazine ring of the ofloxacin structure. As a result, Ofloxacin N-oxide exhibits altered pharmacological properties compared to its parent compound. It is generally recognized for its antibacterial activity, although its efficacy may differ from that of ofloxacin. The compound is typically a white to off-white solid and is soluble in organic solvents, which may influence its bioavailability and distribution in biological systems. In terms of safety, like many fluoroquinolones, it may have associated side effects, and its use should be guided by appropriate medical advice. Research into its specific applications and mechanisms of action continues, contributing to the understanding of its role in antimicrobial therapy.

Formula: C₁₈H₂₀FN₃O₅

InChI: InChI=1S/C18H20FN3O5/c1-10-9-27-17-14-11(16(23)12(18(24)25)8-21(10)14)7-13(19)15(17)20-3-5-22(2,26)6-4-20/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)

InChI key: InChIKey=MVLAUMUQGRQERL-UHFFFAOYSA-N

SMILES: O=C1C=2C3=C(C(=C(F)C2)N4CCN(C)(=O)CC4)OCC(C)N3C=C1C(O)=O

Synonyms:

• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, N-oxide, (±)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-
• 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Aci
• 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Acetic Acid Salt
• 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
• Ofloxacin N-Oxide Acetic Acid Salt (Mixture of Diastereomers)
• Ofloxacin N-oxide

Ofloxacin EP Impurity F (Ofloxacin N-Oxide)

CAS: 104721-52-0

Formula: C₁₈H₂₀FN₃O₅

Color and Shape: White To Off-White Solid

Molecular weight: 377.37

Ref: 4Z-O-034001

9-Fluoro-3-Methyl-10-(4-Methyl-4-Oxido-1-Piperazinyl)-7-Oxo-

CAS: 104721-52-0

9-Fluoro-3-Methyl-10-(4-Methyl-4-Oxido-1-Piperazinyl)-7-Oxo--N-[2-[(2,6,6,-Trimethylcyclohexyl)Amino]Ethyl]-9H Fluoropyridinium Chloride is a pharmacokinetic compound that is used as an antibacterial drug. It has been shown to inhibit the bacterial enzyme gyrase, which is required for DNA replication. 9FMOC exhibits stereoselective inhibition of gyrase and other enzymes. The pharmacokinetic properties of 9FMOC have been determined in human blood samples and urine samples. 9FMOC is metabolized to form an N‑oxide in vivo, which may contribute to its antibacterial activity.

Formula: C₂₀H₂₄FN₃O₇

Purity: Min. 95%

Molecular weight: 437.42 g/mol

Ref: 3D-FF103842

Ofloxacin EP Impurity F

CAS: 104721-52-0

Formula: C₁₈H₂₀FN₃O₅

Molecular weight: 377.37

Ref: ST-EA-CP-O5006