CAS 104746-04-5: Eslicarbazepine

Description: Eslicarbazepine, with the CAS number 104746-04-5, is an antiepileptic drug primarily used in the treatment of partial-onset seizures. It is a derivative of carbamazepine and functions as a voltage-gated sodium channel blocker, which helps stabilize neuronal membranes and reduce excessive neuronal firing. The chemical structure of eslicarbazepine includes a carbamate moiety, contributing to its pharmacological properties. It is typically administered in its active form, which is the S-enantiomer of the racemic mixture of carbazepine. Eslicarbazepine is known for its favorable pharmacokinetic profile, including a relatively long half-life, which allows for once-daily dosing. Additionally, it has a lower potential for drug-drug interactions compared to some other antiepileptic medications. Common side effects may include dizziness, drowsiness, and nausea, but it is generally well-tolerated. Overall, eslicarbazepine represents an important therapeutic option for managing epilepsy, particularly in patients who may not respond adequately to other treatments.

Formula: C₁₅H₁₄N₂O₂

InChI: InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)/t14-/m0/s1

InChI key: InChIKey=BMPDWHIDQYTSHX-AWEZNQCLSA-N

SMILES: O=C(N)N1C=2C=CC=CC2CC(O)C=3C=CC=CC31

Synonyms:

• (10S)-10,11-Dihydro-10-hydroxy Carbamazepine
• (10S)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
• (10S)-10-hydroxy-10,11-Dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
• (S)-(+)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
• (S)-(+)-10,11-Dihydro-10-hydroxy-5H-dibenzo[b,f]azepine-5-carboxamide
• (S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
• (S)-Licarbazepine
• 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-, (10S)-
• 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-, (S)-
• Bia 2-194
• Cgp 13751
• Erelib
• Eslicarbazepine
• Pazzul
• S-(+)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide,S-MHD
• Stedesa

(S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

CAS: 104746-04-5

• Formula: C₁₅H₁₄N₂O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 254.2839

(S)-Licarbazepine-d4

CAS: 104746-04-5

• Formula: C₁₅H₁₀D₄N₂O₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 258.31

(S)-Licarbazepine

CAS: 104746-04-5

• Formula: C₁₅H₁₄N₂O₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 254.29

(S)-10-Monohydroxy-10,11-dihydro carbamazepine

CAS: 104746-04-5

(S)-10-Monohydroxy-10,11-dihydro carbamazepine is a prodrug that is metabolized to carbamazepine. It has been shown to …

• Formula: C₁₅H₁₄N₂O₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 254.28 g/mol

(S)-10-Monohydroxy-10,11-dihydro Carbamazepine (Eslicarbazepine)

CAS: 104746-04-5

Applications (S)-10-Monohydroxy-10,11-dihydro Carbamazepine is the metabolite of Eslicarbazepine acetate, (BIA 2-093), (E659000) a novel central …

• Formula: C₁₅H₁₄N₂O₂
• Color and Shape: Off White
• Molecular weight: 254.28

(S)-10-Monohydroxy-10,11-dihydro Carbamazepine-D3 (Eslicarbazepine-D3)

CAS: 104746-04-5

Applications (S)-10-Monohydroxy-10,11-dihydro Carbamazepine-D3 is a labelled analogue of (S)-10-Monohydroxy-10,11-dihydro Carbamazepine (M546510), a metabolite of Eslicarbazepine …

• Formula: C₁₅H₁₁D₃N₂O₂
• Color and Shape: White To Off-White
• Molecular weight: 257.3

Eslicarbazepine

CAS: 104746-04-5

Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.

• Formula: C₁₅H₁₄N₂O₂
• Purity: 99.23%
• Color and Shape: Off-White Solid
• Molecular weight: 254.28