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Barnidipine Hydrochloride

CAS 104757-53-1: Barnidipine Hydrochloride

Description:Barnidipine Hydrochloride is a calcium channel blocker primarily used in the treatment of hypertension. It belongs to the dihydropyridine class of compounds, which are characterized by their ability to selectively inhibit calcium influx through L-type calcium channels in vascular smooth muscle and cardiac tissue. This action leads to vasodilation and a subsequent decrease in blood pressure. Barnidipine is known for its long half-life, allowing for once-daily dosing, which can enhance patient compliance. The hydrochloride salt form improves its solubility and bioavailability. In terms of its chemical structure, Barnidipine features a dihydropyridine ring, which is essential for its pharmacological activity. Additionally, it exhibits a favorable side effect profile, with a lower incidence of reflex tachycardia compared to some other calcium channel blockers. As with any medication, it is important to consider potential interactions and contraindications, and it should be used under medical supervision to ensure safety and efficacy.

Formula:C27H30ClN3O6

InChI:InChI=1S/C27H29N3O6.ClH/c1-17-23(26(31)35-3)25(20-10-7-11-21(14-20)30(33)34)24(18(2)28-17)27(32)36-22-12-13-29(16-22)15-19-8-5-4-6-9-19;/h4-11,14,22,25,28H,12-13,15-16H2,1-3H3;1H/t22-,25-;/m0./s1

InChI key:InChIKey=XEMPUKIZUCIZEY-YSCHMLPRSA-N

SMILES:Cl.O=C(OC)C1=C(NC(=C(C(=O)OC2CN(CC=3C=CC=CC3)CC2)C1C=4C=CC=C(C4)N(=O)=O)C)C

  • Synonyms:
  • (+)-(3'S,4S)-1-Benzyl-3-Pyrrolidinyl Methyl 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-3,5-Pyridinedicarboxylate
  • (3S)-1-benzylpyrrolidin-3-yl methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride (1:1)
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-[(3S)-1-(phenylmethyl)-3-pyrrolidinyl] ester, hydrochloride (1:1), (4S)-
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl (3S)-1-(phenylmethyl)-3-pyrrolidinyl ester, monohydrochloride, (4S)-
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 1-(phenylmethyl)-3-pyrrolidinyl ester, monohydrochloride, [S-(R*,R*)]-
  • Barnidipine Hcl
  • Hydrochloride,(S-(R*,R*))-Hyl1-(Phenylmethyl)-3-Pyrrolidinyleste
  • Ly198561
  • Mepirodipinehydrochloride
  • Ym 09730-5
  • See more synonyms
  • Ym09730-5
  • Ym730
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Barnidipine hydrochloride

CAS:104757-53-1

Ref: IN-DA007XK5

1g542.00 €
100mg114.00 €
250mg153.00 €
Estimated delivery in United States, on Wednesday 5 Mar 2025
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Barnidipine hydrochloride

CAS:104757-53-1

Ref: 7W-GP6852

Undefined sizeTo inquire
Estimated delivery in United States, on Thursday 6 Mar 2025
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Barnidipine HCl

CAS:104757-53-1

Ref: 4Z-B-415

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100mgTo inquire
Estimated delivery in United States, on Thursday 6 Mar 2025
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Barnidipine-d5 HCl

CAS:104757-53-1

Ref: 4Z-B-411

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Estimated delivery in United States, on Thursday 6 Mar 2025
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Barnidipine hydrochloride

CAS:104757-53-1

Ref: TM-T5856

25mg35.00 €
50mg42.00 €
100mg58.00 €
1mL*10mM (DMSO)35.00 €
Estimated delivery in United States, on Wednesday 12 Mar 2025
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Barnidipine Hydrochloride

CAS:104757-53-1

Ref: TR-B118700

5mg127.00 €
25mg182.00 €
100mg260.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
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Barnidipine hydrochloride

CAS:104757-53-1

Ref: 3D-FB18144

100mg242.00 €
250mg470.00 €
Estimated delivery in United States, on Tuesday 18 Mar 2025
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Barnidipine-d5 Hydrochloride

Controlled Product
CAS:104757-53-1

Ref: TR-B118703

75mg16,483.00 €
Estimated delivery in United States, on Tuesday 15 Apr 2025
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