CAS 10477-72-2

4-[Bis(2-chloroethyl)amino]benzeneacetic acid

Description:

4-[Bis(2-chloroethyl)amino]benzeneacetic acid, with the CAS number 10477-72-2, is a chemical compound that features a benzene ring substituted with a bis(2-chloroethyl)amino group and an acetic acid moiety. This compound is characterized by its potential use in medicinal chemistry, particularly in the development of anticancer agents due to its alkylating properties. The presence of the chloroethyl groups allows for the formation of reactive intermediates that can interact with nucleophilic sites in biological molecules, such as DNA. The carboxylic acid functional group contributes to its solubility in polar solvents and may influence its biological activity. Additionally, the compound's structure suggests it may exhibit both lipophilic and hydrophilic characteristics, which can affect its pharmacokinetics and bioavailability. Safety and handling precautions are essential due to the presence of chlorine atoms, which can pose health risks. Overall, this compound is of interest in the field of pharmaceutical research, particularly for its potential therapeutic applications.

Formula: C₁₂H₁₅Cl₂NO₂

InChI: InChI=1S/C12H15Cl2NO2/c13-5-7-15(8-6-14)11-3-1-10(2-4-11)9-12(16)17/h1-4H,5-9H2,(H,16,17)

InChI key: InChIKey=RQAFMLCWWGDNLI-UHFFFAOYSA-N

SMILES: N(CCCl)(CCCl)C1=CC=C(CC(O)=O)C=C1

Synonyms:

• (4-(Bis(2-chloroethyl)amino)phenyl)acetic acid
• (p-(Bis(2-chloroethyl)amino)phenyl)acetic acid
• 1-(2-Chlorophenyl)Ethanone
• 2-(p-(Bis(2-chloroethyl)amino)phenyl)acetic acid
• 4-(Bis(2-chloroethyl)amino)benzeneacetic acid
• 4-[N,N-Bis(2-chloroethyl)amino]phenylacetic acid
• Acetic acid, (p-(bis(2-chloroethyl)amino)phenyl)-
• Acetic acid, (p-(bis(2-chloroethyl)amino)phenyl)- (8CI)
• Acetic acid, 2-(p-(bis(2-chloroethyl)amino)phenyl)-
• Benzeneacetic acid, 4-(bis(2-chloroethyl)amino)- (9CI)
• Benzeneacetic acid, 4-[bis(2-chloroethyl)amino]-
• Brn 0960062
• Cb 1331
• Chlorophenacyle
• Chlorphenacil
• Chlorphenacyl
• Khlorfenatsil
• N,N-Bis(2-chloroethyl)-p-aminophenylacetic acid
• N,N-Bis(chloroethyl)-p-aminophenylacetic acid
• Nsc 71964
• Paam
• Phenylacetic acid mustard
• Phenylacetic mustard
• [p-Bis(2-chloroethyl)aminophenyl]acetic acid
• p-(N,N-Di(2-chloroethyl)amino)phenylacetic acid
• p-N,N-(Dichloroethyl)aminophenylacetic acid
• p-N,N-Di-(2-chloroethyl)aminophenyl acetic acid
• 4-14-00-01313 (Beilstein Handbook Reference)

Phenylacetic acid mustard-d8

CAS: 10477-72-2

Formula: C₁₂H₇Cl₂NO₂D₈

Color and Shape: Off-White Solid

Molecular weight: 284.21

Ref: 4Z-C-614

Phenylacetic Acid Mustard

CAS: 10477-72-2

Formula: C₁₂H₁₅Cl₂NO₂

Color and Shape: Off-White Solid

Molecular weight: 276.16

Ref: 4Z-C-613

2-{4-[di(2-chloroethyl)amino]phenyl}acetic acid

CAS: 10477-72-2

2-{4-[di(2-chloroethyl)amino]phenyl}acetic acid

Purity: ≥95%

Molecular weight: 276.16g/mol

Ref: 54-OR26171

Phenylacetic Mustard

Controlled Product

CAS: 10477-72-2

Formula: C₁₂H₁₅Cl₂NO₂

Color and Shape: Neat

Molecular weight: 276.159

Ref: TR-P319190

4-(Bis-phenylacetic acid

CAS: 10477-72-2

4-(Bis-phenylacetic acid) is a synthetic peptide that activates the ion channel TRPV1, which is involved in pain transmission. It has been shown to be a potent inhibitor of protein interactions and may be used as a research tool for the study of protein interactions. 4-(Bis-phenylacetic acid) has been shown to inhibit the activity of ion channels such as TRPV1, TRPM8, and TRPA1.

Formula: C₁₂H₁₅Cl₂NO₂

Purity: Min. 95%

Molecular weight: 276.16 g/mol

Ref: 3D-KAA47772

Phenylacetic Acid Mustard

CAS: 10477-72-2

Formula: C₁₂H₁₅Cl₂NO₂

Molecular weight: 276.16

Ref: ST-EA-CP-P42001