CAS 10488-36-5

Ethanamine, N-methyl-2-[(2-methylphenyl)phenylmethoxy]-, hydrochloride (1:1)

Description:

Ethanamine, N-methyl-2-[(2-methylphenyl)phenylmethoxy]-, hydrochloride (1:1), commonly referred to as a hydrochloride salt, is a chemical compound characterized by its amine functional group and ether linkage. This substance features a central ethanamine structure with a methyl group attached to the nitrogen atom, enhancing its basicity and solubility in polar solvents. The presence of the 2-methylphenyl and phenylmethoxy groups contributes to its hydrophobic characteristics, potentially influencing its biological activity and interaction with other molecules. As a hydrochloride salt, it is typically more stable and soluble in aqueous solutions compared to its free base form. This compound may exhibit pharmacological properties, making it of interest in medicinal chemistry, although specific biological activities would depend on its structure and the context of its use. Safety data and handling precautions should be observed, as with any chemical substance, particularly those with potential biological activity.

Formula: C₁₇H₂₁NO·ClH

InChI: InChI=1S/C17H21NO.ClH/c1-14-8-6-7-11-16(14)17(19-13-12-18-2)15-9-4-3-5-10-15;/h3-11,17-18H,12-13H2,1-2H3;1H

InChI key: InChIKey=YAXWIYFUVISXRS-UHFFFAOYSA-N

SMILES: C(OCCNC)(C1=C(C)C=CC=C1)C2=CC=CC=C2.Cl

Synonyms:

• (2-(Phenyl-o-tolylmethoxy)ethyl)methylamine hydrochloride
• BS 7331 hydrochloride
• Bs 7331
• Elamol
• Ethanamine, N-methyl-2-((2-methylphenyl)phenylmethoxy)-, hydrochloride
• Ethanamine, N-methyl-2-[(2-methylphenyl)phenylmethoxy]-, hydrochloride (1:1)
• Ethylamine, N-methyl-2-((o-methyl-alpha-phenylbenzyl)oxy)-, hydrochloride
• Ethylamine, N-methyl-2-[(o-methyl-α-phenylbenzyl)oxy]-, hydrochloride
• N-Demethylorphenadrine hydrochloride
• N-Methyl-2-((o-methyl-alpha-phenylbenzyl)oxy)ethylamine hydrochloride
• N-Methyl-2-(alpha-(2-tolylbenzyl)oxy)ethylamine hydrochloride
• N-Methylaminoethyl 2-methylbenzhydryl ether hydrochloride
• N-methyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanaminium chloride
• Nsc 113809
• Nsc 169432
• Phenyl-(o-tolylmethyl) methylaminoethyl ether hydrochloride
• Tofacine
• Tofenacin HCl
• Tofenacin hydrochloride [USAN]
• Tofenacine
• Tofenacine hydrochloride
• Unii-3A10Nd4Dwr

Orphenadrine Related Compound C (N-methyl-2-[phenyl(o-tolyl)methoxy]ethanamine hydrochloride)

CAS: 10488-36-5

Aromatic drugs of amino-alcohols, other than those contg more than one kind of oxygen function, their ethers and esters; salts thereof, nesoi

Formula: C₁₇H₂₁NO·ClH

Color and Shape: White Off-White Powder

Molecular weight: 291.13899

Ref: 45-1479031

Orphenadrine USP Related Compound C (N-Desmethyl Orphenadrine HCl, Tofenacin HCl)

CAS: 10488-36-5

Formula: C₁₇H₂₁NO·HCl

Color and Shape: Off-White Solid

Molecular weight: 255.36 36.46

Ref: 4Z-O-053

Orphenadrine USP Related Compound C (as Hydrochloride)

Controlled Product

CAS: 10488-36-5

Formula: C₁₇H₂₁NO·ClH

Color and Shape: Neat

Molecular weight: 291.82

Ref: 86-MM0801.07

Tofenacin Hydrochloride Salt

Controlled Product

CAS: 10488-36-5

Applications A metabolite of Orphenadrine (O695300). An antidepressant prodrug. Ondansetron USP Related Compound C.
References Watkins, P., et al.: J. Biol. Chem., 261, 6264 (1986), McNeil, C., et al.: Biochem. Pharmacol., 51, 15 (1996), Hiessbock, R., et al.: J. Med. Chem., 42, 1921 (1999),

Formula: C₁₇H₂₁NO·ClH

Color and Shape: Neat

Molecular weight: 291.82

Ref: TR-T528500

Tofenacin Hydrochloride Salt-d4

Controlled Product

CAS: 10488-36-5, 1330239-94-5

Applications A labelled metabolite of Orphenadrine (O695300). An antidepressant prodrug.
References Watkins, P., et al.: J. Biol. Chem., 261, 6264 (1986), McNeil, C., et al.: Biochem. Pharmacol., 51, 15 (1996), Hiessbock, R., et al.: J. Med. Chem., 42, 1921 (1999),

Formula: C₁₇H₁₈D₄ClNO

Color and Shape: Neat

Molecular weight: 295.84

Ref: TR-T528502

Tofenacin hydrochloride

CAS: 10488-36-5

Tofenacin hydrochloride: a tricyclic-like SNRI antidepressant with potential anticholinergic and antihistamine effects, linked to Parkinson's relief.

Formula: C₁₇H₂₂ClNO

Color and Shape: Solid

Molecular weight: 291.82

Ref: TM-T71537