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CAS 1049978-59-7

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(3S,4R)-4-(2-(Trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid

Description:
The chemical substance known as (3S,4R)-4-(2-(Trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid, with the CAS number 1049978-59-7, is a chiral pyrrolidine derivative characterized by a pyrrolidine ring substituted at the 4-position with a 2-(trifluoromethyl)phenyl group and a carboxylic acid functional group at the 3-position. This compound exhibits significant biological activity, often studied for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. The presence of the trifluoromethyl group enhances lipophilicity and metabolic stability, which can influence the compound's pharmacokinetic properties. The specific stereochemistry, indicated by the (3S,4R) configuration, is crucial for its biological interactions, as chirality can greatly affect the efficacy and safety of drug candidates. Additionally, the carboxylic acid group contributes to the compound's acidity and solubility in polar solvents, making it relevant for various chemical reactions and formulations. Overall, this compound represents a valuable scaffold in drug discovery and development.
Formula:C12H12F3NO2
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