CAS 10500-64-8

4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol

Description:

4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol, with the CAS number 10500-64-8, is a chemical compound characterized by its quinoline structure, which contributes to its biological activity. This compound features a pentanol chain, indicating the presence of a hydroxyl (-OH) group, which enhances its solubility in polar solvents. The chloro substituent on the quinoline ring can influence its reactivity and interaction with biological targets. Typically, compounds of this nature may exhibit pharmacological properties, potentially acting as antimicrobial or antitumor agents, although specific biological activities would depend on further empirical studies. The presence of both an amino group and a hydroxyl group suggests that it may participate in hydrogen bonding, affecting its physical properties such as melting point and boiling point. Additionally, the compound's structural features may allow for various synthetic modifications, making it of interest in medicinal chemistry and drug development. Safety and handling precautions should be observed, as with any chemical substance, due to potential toxicity or reactivity.

Formula: C₁₄H₁₇ClN₂O

InChI: InChI=1S/C14H17ClN2O/c1-10(3-2-8-18)17-13-6-7-16-14-9-11(15)4-5-12(13)14/h4-7,9-10,18H,2-3,8H2,1H3,(H,16,17)

InChI key: InChIKey=BZUKCXDUDOUBKN-UHFFFAOYSA-N

SMILES: N(C(CCCO)C)C=1C2=C(N=CC1)C=C(Cl)C=C2

Synonyms:

• 1-Pentanol, 4-[(7-chloro-4-quinolyl)amino]-
• 1-Pentanol, 4-[(7-chloro-4-quinolinyl)amino]-
• 4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol

1-Pentanol, 4-[(7-chloro-4-quinolinyl)amino]-

CAS: 10500-64-8

Formula: C₁₄H₁₇ClN₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 264.7506

Ref: IN-DA0085HD

Hydroxychloroquine Sulfate EP Impurity E

CAS: 10500-64-8

Formula: C₁₄H₁₇ClN₂O

Color and Shape: White To Off-White Solid

Molecular weight: 264.75

Ref: 4Z-H-0619

Hydroxychloroquine Impurity E

CAS: 10500-64-8

Hydroxychloroquine Impurity E, a byproduct, can block TLR7/9 and inhibit SARS-CoV-2 in vitro.

Formula: C₁₄H₁₇ClN₂O

Color and Shape: Solid

Molecular weight: 264.75

Ref: TM-T73963

Hydroxychloroquine Impurity E

CAS: 10500-64-8

Hydroxychloroquine Impurity E

Purity: 98%

Ref: 54-OR1036789

4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol

Controlled Product

CAS: 10500-64-8

Applications An intermediate in the preparation of Cletoquine Oxalate and Chloroquinolin
References Singh, T., et al.: J. Med. Chem. 14, 283 (1971),

Formula: C₁₄H₁₇ClN₂O

Color and Shape: Neat

Molecular weight: 264.75

Ref: TR-C381370

Hydroxychloroquine EP Impurity E

CAS: 10500-64-8

Formula: C₁₄H₁₇ClN₂O

Molecular weight: 264.75

Ref: ST-EA-CP-H4005

4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol

CAS: 10500-64-8

4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol (QLT) is a drug that has been shown to be effective against both healthy volunteers and malaria patients. It is a prodrug that is metabolized by the liver into 7-chloroquinalone, which inhibits the growth of plasmodium falciparum. QLT has been shown to be safe and well tolerated in studies with healthy volunteers, and it does not appear to cause significant adverse effects. QLT also has an effect on T cells, which may be due to its ability to inhibit protein synthesis and cell division.

Formula: C₁₄H₁₇ClN₂O

Purity: Min. 95%

Color and Shape: Yellow Solid

Molecular weight: 264.75 g/mol

Ref: 3D-FC20107