CAS 105012-15-5

HYDROXY MIFEPRISTONE

Description:

Hydroxy mifepristone, with the CAS number 105012-15-5, is a synthetic steroid compound that serves as a derivative of mifepristone, a well-known antiprogestin. This substance exhibits properties that allow it to bind to progesterone receptors, thereby inhibiting the effects of progesterone, which is crucial for maintaining pregnancy. Hydroxy mifepristone is characterized by its ability to modulate hormonal activity, making it relevant in reproductive health and therapeutic applications, particularly in medical abortion protocols. The compound is typically administered in a controlled setting due to its potent biological effects. Its chemical structure includes a modified steroid backbone, which contributes to its pharmacological activity. Hydroxy mifepristone is also studied for its potential use in treating conditions such as endometriosis and certain types of cancer, where progesterone plays a significant role in disease progression. As with many pharmacologically active compounds, safety, efficacy, and regulatory considerations are paramount in its use.

Formula: C₂₉H₃₅NO₃

InChI: InChI=1/C29H35NO3/c1-28-18-25(19-5-8-21(9-6-19)30(2)3)27-23-12-10-22(32)17-20(23)7-11-24(27)26(28)13-15-29(28,33)14-4-16-31/h5-6,8-9,17,24-26,31,33H,7,10-13,15-16,18H2,1-3H3/t24-,25+,26-,28-,29+/m0/s1

Synonyms:

• Ru 42698
• (11,17)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(3-hydroxy-1-propyn-1-yl)-estra-4,9-dien-3-one
• 22-Hydroxy Mifepristone
• (11Beta,17Alpha)-11-[4-(Dimethylamino)Phenyl]-17-Hydroxy-17-(3-Hydroxyprop-1-Yn-1-Yl)Estra-4,9-Dien-3-One

Hydroxy Mifepristone

CAS: 105012-15-5

Formula: C₂₉H₃₅NO₃

Color and Shape: Yellow Solid

Molecular weight: 445.60

Ref: 4Z-M-295

Hydroxy Mifepristone-d6

CAS: 105012-15-5

Formula: C₂₉H₂₉D₆NO₃

Color and Shape: Yellow Solid

Molecular weight: 451.64

Ref: 4Z-M-296

22-Hydroxy Mifepristone

Controlled Product

CAS: 105012-15-5

Applications A metabolite of Mifepristone.
References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),

Formula: C₂₉H₃₅NO₃

Color and Shape: Neat

Molecular weight: 445.59

Ref: TR-H948445

22-Hydroxy Mifepristone-d6

Controlled Product

CAS: 105012-15-5

Applications A labelled metabolite of Mifepristone.
References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),

Formula: C₂₉H₂₉D₆NO₃

Color and Shape: Neat

Molecular weight: 451.63

Ref: TR-H948447

22-Hydroxy mifepristone

CAS: 105012-15-5

Please enquire for more information about 22-Hydroxy mifepristone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₉H₃₅NO₃

Purity: Min. 95%

Molecular weight: 445.59 g/mol

Ref: 3D-FH24052

Hydroxy Mifepristone

CAS: 105012-15-5

Formula: C₂₉H₃₅NO₃

Molecular weight: 445.6

Ref: ST-EA-CP-M61009

22-Hydroxy mifepristone

CAS: 105012-15-5

22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcohol metabolite that exhibits both anti-progestational and anti-glucocorticoid activities. This compound contains an alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. Furthermore, 22-Hydroxy Mifepristone demonstrates a relative binding affinity of 48% to the human glucocorticoid receptor.

Formula: C₂₉H₃₅NO₃

Color and Shape: Solid

Molecular weight: 445.59

Ref: TM-T201780