(R,R)-reboxetine (mesylate) is a selective norepinephrine reuptake inhibitor (NRI) primarily used in the treatment of major depressive disorder. It is characterized by its chiral structure, with the (R,R) configuration indicating the specific arrangement of its atoms, which is crucial for its pharmacological activity. The mesylate salt form enhances its solubility and stability, facilitating its use in pharmaceutical formulations. This compound exhibits a high affinity for norepinephrine transporters, leading to increased levels of norepinephrine in the synaptic cleft, which is believed to contribute to its antidepressant effects. In terms of physical properties, (R,R)-reboxetine (mesylate) is typically a white to off-white crystalline powder. It is soluble in water and various organic solvents, making it suitable for various delivery methods. Safety and efficacy profiles are well-studied, but like all medications, it may have side effects and contraindications that should be considered in clinical use. Overall, (R,R)-reboxetine (mesylate) represents a significant advancement in the pharmacotherapy of depression.

(R,R)-reboxetine (Mesylate)

105017-39-8: (R,R)-reboxetine (mesylate) is a selective norepinephrine reuptake inhibitor (NRI) primarily used in the treatment of major depressive disorder. It is characterized by its chiral structure, with the (R,R) configuration indicating the specific arrangement of its atoms, which is crucial for its pharmacological activity. The mesylate salt form enhances its solubility and stability, facilitating its use in pharmaceutical formulations. This compound exhibits a high affinity for norepinephrine transporters, leading to increased levels of norepinephrine in the synaptic cleft, which is believed to contribute to its antidepressant effects. In terms of physical properties, (R,R)-reboxetine (mesylate) is typically a white to off-white crystalline powder. It is soluble in water and various organic solvents, making it suitable for various delivery methods. Safety and efficacy profiles are well-studied, but like all medications, it may have side effects and contraindications that should be considered in clinical use. Overall, (R,R)-reboxetine (mesylate) represents a significant advancement in the pharmacotherapy of depression.

<p>(R,R)-Reboxetine mesylate: Antidepressant, high bioavailability, (R,R) enantiomer, selective for noradrenaline, low toxicity.</p>

CAS 105017-39-8

(R,R)-reboxetine (Mesylate)

(R,R)-Reboxetine mesylate

Ref: TM-T72209