PEG13-Tos, or polyethylene glycol tosylate, is a chemical compound characterized by its structure, which includes a polyethylene glycol (PEG) chain and a tosyl (p-toluenesulfonyl) group. This compound typically exhibits properties such as solubility in polar solvents, making it useful in various applications, including pharmaceuticals and bioconjugation. The presence of the tosyl group enhances its reactivity, allowing it to participate in nucleophilic substitution reactions, which is valuable in organic synthesis. PEG13-Tos is often utilized as a linker or reagent in the development of drug delivery systems and in the modification of biomolecules. Its molecular weight and hydrophilicity contribute to its ability to improve the solubility and stability of compounds in aqueous environments. Additionally, PEG derivatives are known for their biocompatibility, making PEG13-Tos a suitable candidate for applications in biomedical fields. Overall, PEG13-Tos combines the advantageous properties of PEG with the reactivity of the tosyl group, facilitating its use in various chemical and biological processes.

PEG13-Tos is a PEG linker containing a hydroxyl group and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

PEG13-Tos

1050500-41-8: PEG13-Tos, or polyethylene glycol tosylate, is a chemical compound characterized by its structure, which includes a polyethylene glycol (PEG) chain and a tosyl (p-toluenesulfonyl) group. This compound typically exhibits properties such as solubility in polar solvents, making it useful in various applications, including pharmaceuticals and bioconjugation. The presence of the tosyl group enhances its reactivity, allowing it to participate in nucleophilic substitution reactions, which is valuable in organic synthesis. PEG13-Tos is often utilized as a linker or reagent in the development of drug delivery systems and in the modification of biomolecules. Its molecular weight and hydrophilicity contribute to its ability to improve the solubility and stability of compounds in aqueous environments. Additionally, PEG derivatives are known for their biocompatibility, making PEG13-Tos a suitable candidate for applications in biomedical fields. Overall, PEG13-Tos combines the advantageous properties of PEG with the reactivity of the tosyl group, facilitating its use in various chemical and biological processes.

Tos-PEG12 is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

CAS 1050500-41-8

PEG13-Tos

PEG13-Tos

Ref: IN-DA00HAKN

PEG12-Tos

Ref: TM-T16452