CAS 105093-21-8

CIPROFLOXACIN PIPERAZINYL-N4-SULFATE

Description:

Ciprofloxacin piperazinyl-N4-sulfate, with the CAS number 105093-21-8, is a synthetic antibiotic belonging to the fluoroquinolone class. It is primarily used for its broad-spectrum antibacterial activity against a variety of Gram-negative and some Gram-positive bacteria. The compound exhibits a mechanism of action that involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. This results in the disruption of bacterial cell division and ultimately leads to cell death. Ciprofloxacin piperazinyl-N4-sulfate is characterized by its solubility in water and its stability under various pH conditions, making it suitable for both oral and intravenous administration. It is often utilized in the treatment of infections such as urinary tract infections, respiratory tract infections, and skin infections. However, like other fluoroquinolones, it may be associated with side effects, including gastrointestinal disturbances and potential effects on tendon health. Its use is generally guided by susceptibility patterns and clinical guidelines to ensure effective treatment while minimizing resistance development.

Formula: C₁₇H₁₈FN₃O₆S

InChI: InChI=1/C17H18FN3O6S/c18-13-7-11-14(21(10-1-2-10)9-12(16(11)22)17(23)24)8-15(13)19-3-5-20(6-4-19)28(25,26)27/h7-10H,1-6H2,(H,23,24)(H,25,26,27)

SMILES: C1CC1n1cc(c(=O)c2cc(c(cc12)N1CCN(CC1)S(=O)(=O)O)F)C(=O)O

Synonyms:

• Sulfo-Ciprofloxacin
• (Sulfociprofloxacin, 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-sulfo-1-piperazinyl)-3-quinolinecarboxylic Acid
• 4-Sulfociprofloxacin
• BAY-s 9435)
• 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-sulfo-1-piperazinyl)-3-quinolinecarboxylic Acid
• 1-Cyclopropyl-6-Fluoro-4-Oxo-7-(4-Sulfopiperazin-1-Yl)-1,4-Dihydroquinoline-3-Carboxylic Acid

Sulfociprofloxacin Sodium Salt

CAS: 105093-21-8

Formula: C₁₇H₁₇FN₃O₆S·Na

Color and Shape: Pale Yellow Solid

Molecular weight: 410.40 22.99

Ref: 4Z-C-083

Ciprofloxacin Piperazinyl-N4-sulfate

CAS: 105093-21-8

Applications A metabolite of the fluorinated quinolone antibacterial Ciprofloxacin (C482500).
References Hoffken, G., et al.: Antimicrob. Ag. Chemother., 27, 375 (1985), Scully, B.E., et al.: Lancet, 1, 819 (1986)

Formula: C₁₇H₁₈FN₃O₆S

Color and Shape: Neat

Molecular weight: 411.40

Ref: TR-C482525

Ciprofloxacin piperazinyl-N4-sulfate

CAS: 105093-21-8

Ciprofloxacin is a fluoroquinolone antibiotic with potent activity against many Gram-negative and Gram-positive bacteria. It is used in the treatment of urinary tract infections, respiratory tract infections, skin and soft tissue infections, bone and joint infections, and intra-abdominal infections. Ciprofloxacin piperazinyl-N4-sulfate has the potential to interact with other drugs. It binds to human serum albumin (HSA) and may be excreted into breast milk. The drug is well absorbed orally but has poor bioavailability due to rapid metabolism by the liver. Ciprofloxacin piperazinyl-N4-sulfate has been shown to have pharmacokinetic properties that are independent of dose or duration of administration.

Formula: C₁₇H₁₈FN₃O₆S

Purity: Min. 95%

Molecular weight: 411.41 g/mol

Ref: 3D-FC20456

Ciprofloxacin Piperazinyl-N4-sulfate

CAS: 105093-21-8

Formula: C₁₇H₁₈FN₃O₆S

Molecular weight: 411.4

Ref: ST-EA-CP-C22047