CAS 105107-84-4

cis-4-Phenylthio-L-proline hydrochloride

Description:

Cis-4-Phenylthio-L-proline hydrochloride is a chemical compound characterized by its unique structural features and properties. It is a derivative of proline, an amino acid, with a phenylthio group attached at the 4-position, which influences its biological activity and solubility. The "cis" configuration indicates that the substituents around the proline ring are oriented on the same side, which can affect its conformation and interactions with biological targets. As a hydrochloride salt, it is typically more soluble in water compared to its free base form, enhancing its utility in various applications, particularly in pharmaceutical research. This compound is of interest in the study of peptide synthesis and may exhibit specific pharmacological properties due to its structural characteristics. Its CAS number, 105107-84-4, allows for precise identification in chemical databases and literature. Overall, cis-4-Phenylthio-L-proline hydrochloride serves as a valuable compound in both synthetic chemistry and medicinal chemistry research.

Formula: C₁₁H₁₄ClNO₂S

InChI: InChI=1/C11H13NO2S.ClH/c13-11(14)10-6-9(7-12-10)15-8-4-2-1-3-5-8;/h1-5,9-10,12H,6-7H2,(H,13,14);1H/t9-,10-;/m0./s1

SMILES: c1ccc(cc1)S[C@H]1C[C@@H](C(=O)O)NC1.Cl

Synonyms:

• (4S)-4-(Phenylthio)-L-proline hydrochloride
• (4S)-4-(phenylsulfanyl)-L-proline hydrochloride (1:1)

Zofenopril Impurity 2

CAS: 105107-84-4

Formula: C₁₁H₁₃NO₂SHCl

Molecular weight: 223.29 : 36.46

Ref: ST-EA-CP-Z22003

cis-4-Phenylthio-L-proline hydrochloride

CAS: 105107-84-4

Formula: C₁₁H₁₄ClNO₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 259.7524

Ref: IN-DA007X2X

Cis-4-Phenylthio-L-Proline Hydrochloride

CAS: 105107-84-4

Cis-4-Phenylthio-L-Proline Hydrochloride

Purity: 98%

Molecular weight: 259.75g/mol

Ref: 54-OR1012689

(4S)-4-(Phenylthio)-L-proline Hydrochloride

CAS: 105107-84-4

Applications (4S)-4-(Phenylthio)-L-proline is an impurity of Zofenopril (Z587000).
References Krapcho, J., et al.: J. Med. Chem., 31, 1148 (1988),

Formula: C₁₁H₁₄ClNO₂S

Color and Shape: Neat

Molecular weight: 259.75

Ref: TR-P337055

cis-4-Phenylthio-L-proline hydrochloride

CAS: 105107-84-4

Formula: C₁₁H₁₄ClNO₂S

Purity: 97%

Molecular weight: 259.75

Ref: 10-F223862

cis-4-Phenylthio-L-prolineHydrochloride

CAS: 105107-84-4

Zofenopril calcium is a potassium-containing salt of zofenopril, a prodrug that is hydrolyzed in vivo to the active form, 4-phenylthio-L-proline. Zofenopril calcium is used as an antihypertensive agent and has a low incidence of adverse effects. It inhibits the enzyme angiotensin converting enzyme (ACE) in the renin-angiotensin system, which results in decreased levels of angiotensin II and subsequent vasodilation.

Formula: C₁₁H₁₄ClNO₂S

Purity: Min. 95%

Molecular weight: 259.75 g/mol

Ref: 3D-FP152306